Results 81 to 90 of about 2,178 (240)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Modelo matemático de un sistema coordinado productor-comprador bajo el enfoque VMI

Ingeniería, 2012
En este trabajo se desarrolla un nuevo modelo matemático de un sistema coordinado productor-comprador mediante un acuerdo de inventarios administrados por el vendedor (VMI).
Fidel Torres, Frank Ballesteros, Marcela Villa   +2 more
doaj  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Considerando la adopción efectiva de sistemas agrícolas en el diseño de esquemas para la promoción en el cultivo de árboles, Costa Rica

Ciencias Ambientales
[Introducción]: El cultivo actual de árboles es insuficiente para cubrir la demanda nacional de madera, de este modo, los pequeños productores se tornan como una alternativa de solución ante esta situación, ya que pese a contar con áreas pequeñas, en el
Víctor Meza-Picado, Monserrat Romero-Mora, Ronnie de Camino-Velozo, Alfonso Barrantes-Rodríguez   +3 more
doaj   +1 more source

Vacunación frente al herpes zóster. [PDF]

Aten Primaria, 2023
Javierre AP, Sánchez Hernández C, Aldaz P, Grupo de Prevención de Enfermedades Infecciosas del PAPPS-semFYC.   +3 more
europepmc   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

[School nurse and educational innovation to teach cardiopulmonary resuscitation at school through a Flipped Classroom]. [PDF]

Aten Primaria, 2023
Mendoza López M, Pérez Rubio MT, Truque Díaz C, Pardo Ríos M.   +3 more
europepmc   +1 more source

Productor de espárragos

, 2019
Realizan el manejo técnico productivo del cultivo de espárrago, respetando las buenas prácticas agrícolas, normas técnicas de producción, normas de seguridad y salud en el trabajo, con responsabilidad ...
openaire   +1 more source

Conversatorio en red con productores

, 2021
Fil: Iriarte, Daniela Beatriz. Instituto Nacional de Tecnología Agropecuaria (INTA).
Fernandez Valdes, María, Iriarte, Daniela Beatriz   +1 more
openaire   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source