Results 101 to 110 of about 993 (203)
ABSTRACT Relapsed and refractory multiple myeloma (RRMM) remains associated with poor outcomes, particularly in patients exposed or refractory to proteasome inhibitors, immunomodulatory agents, and anti‐CD38 monoclonal antibodies. Targeting B‐cell maturation antigen (BCMA) has emerged as an effective therapeutic strategy, prompting the development of ...
Maria Eugenia Alvaro +12 more
wiley +1 more source
Abstract This paper presents a two‐stage model for planning a renewable energy portfolio by balancing economic, social and environmental sustainability goals. The first stage addresses a multi‐objective problem where conflictive impacts generated by the energy portfolios should be optimised according to the corresponding economic, social or ...
Amelia Bilbao‐Terol +2 more
wiley +1 more source
Automation and Augmentation in Theological Perspective
Abstract AI enables forms of automation that threaten unemployment and deskilling, eliminating important opportunities for the development of virtue. The concomitant loss of virtue and meaningful employment makes it a theological problem from the perspective of Catholic social teaching and theological anthropology.
Paul Scherz
wiley +1 more source
Cohomology of solvable saturable pro‐p$p$ groups and Lie algebras
Abstract Let p$p$ be an odd prime and let n∈N$n\in \mathbb {N}$ be an integer. We show that the n-th$n{\text{-th}}$ mod‐p$p$ cohomology of a solvable saturable pro‐p$p$ group is isomorphic to the n-th$n{\text{-th}}$ mod‐p$p$ cohomology of its associated Zp$\mathbb {Z}_p$‐Lie algebra g$\mathfrak {g}$ as an Fp$\mathbb {F}_p$‐vector space.
Oihana Garaialde Ocaña +2 more
wiley +1 more source
On the Lang–Trotter conjecture for Siegel modular forms
Abstract Let f$f$ be a genus‐two cuspidal Siegel eigenform. We prove an adelic open image theorem for the compatible system of Galois representations associated with f$f$, generalizing the results of Ribet and Momose for elliptic modular forms. Using this result, we investigate the distribution of the Hecke eigenvalues ap$a_p$ of f$f$, and obtain upper
Arvind Kumar, Moni Kumari, Ariel Weiss
wiley +1 more source
This review examines how in vitro electrical and mechanical stimulation modulates wound healing in fibroblasts and keratinocytes. Analyzing over 560 experimental data points, we relate stimulation parameters to proliferation and migration outcomes, evaluate platform designs, and highlight the need for multi‐parameter optimization to advance targeted ...
Matthew K. Burgess +3 more
wiley +1 more source
Vorinostat Potentiates Chemoimmunotherapy in Immune‐Enriched Pancreatic Cancer
Immune‐enriched pancreatic cancer does not confer a significant survival advantage. SAHA sensitizes these “hot” tumors to chemoimmunotherapy by disrupting a FASN/PARP9‐driven “metabolic trap” and enhancing CD8+ T cell function. A CD8high/FASNhigh/PARP9high signature identifies patients who are most likely to benefit from the “gemcitabine‐nivolumab‐SAHA”
Chen Chen +13 more
wiley +1 more source
Wrinkle‐Adaptive Kirigami Wearables With Anisotropic Deformability for Sleep EEG Monitoring
This article introduces a wrinkle‐adaptive, kirigami‐structured wearable EEG patch that personalizes electrode‐skin conformity to stabilize the interface and enable wireless, high‐quality sleep monitoring. ABSTRACT Wearable electroencephalography (EEG) devices offer a promising solution for continuous brain monitoring outside laboratory settings ...
Jungmin Kim +5 more
wiley +1 more source

