Results 21 to 30 of about 34,037 (134)
Synthesis of triazol derivatives of lupeol with potential antimalarial activity
The goal of this project is synthesize and characterization of derivatives of lupeol and evaluated antimalarial activity. Historically, plants are important source of antimalarial medicines, highlighting quinine (1) (Figure 1), an important alkaloid
Tatiane Freitas Borgati +4 more
doaj +1 more source
Is it Fabry disease? Diagnostic and follow-up approach [PDF]
A doença de Anderson-Fabry (DAF) é uma doença sistémica de sobrecarga lisossomal causada por mutações patogénicas do gene GLA (cromossoma X) que condicionam diminuição ou ausência α-galactosidase A e acumulação de globotriaosilceramida (Gb3) e outros ...
Aguiar, Patricio +5 more
core +2 more sources
Evaluation of Brain SPECT with 99mTc‐TRODAT‐1 in the Differential Diagnosis of Parkinsonism
Introduction. Brain SPECT with 99mTc‐TRODAT‐1 (SPECT‐TRODAT) may be a useful tool in the differential diagnosis of Parkinsonism. Objective. To compare results of SPECT‐TRODAT with clinical findings in patients with Parkinsonism. Methods. We evaluated 153 outpatients.
Giorgio Fabiani +5 more
wiley +1 more source
Polymer-based eye drops are the most used drug delivery system to treat dry eye disease (DED). Therefore, the mucoadhesion between the polymer and the ocular mucin is crucial to ensure the efficacy of the treatment.
Angélica Graça +4 more
doaj +1 more source
COMPETITIVIDADE DOS PRODUTOS FARMACÊUTICOS E DOS ANTIBIÓTICOS BRASILEIROS NO COMÉRCIO INTERNACIONAL
O Brasil é considerado um dos grandes players no comércio internacional de produtos farmacêuticos, sendo responsável por uma porção significativa da demanda por estes produtos. Porém, grande parte desta demanda precisa ser atendida através de importações,
Priscila de Souza da Silveira +2 more
doaj +1 more source
A total of 28 lapachol-related naphthoquinones with four different scaffolds were synthesized and spectroscopically characterized. In vitro antiplasmodial activity was assayed against the chloroquine-resistant Plasmodium falciparum W2 strain by the ...
Tatiane Freitas Borgati +5 more
doaj +1 more source
This work describes the development and validation of analytical method to assay nerolidol in a hydrophilic matrix of quitosan by UV/visible spectroscopy. The method is based on the formation of purple derivative between nerolidol and vanillin.
Tatiana Gomes Ribeiro +5 more
doaj +1 more source
Two polymorphs of 2-(prop-2-yn-1-yloxy)naphthalene-1,4-dione: solvent-dependent crystallization
The title compound, C13H8O3, crystallizes in two polymorphs, namely the monoclinic (space group P21/c) and triclinic (space group Pī) forms, obtained from N,N-dimethylformamide and isopropyl alcohol solutions, respectively.
Flaviano Melo Ottoni +3 more
doaj +1 more source
Behavioral and cardiopulmonary effects of dexmedetomidine alone and in combination with butorphanol, methadone, morphine or tramadol in conscious sheep [PDF]
Objective: To compare cardiopulmonary and sedative effects following administration of dexmedetomidine alone or with butorphanol, methadone, morphine or tramadol in healthy sheep. Study design: Randomized crossover study. Animals: Six Santa Inês
Auckburally, Adam +5 more
core +1 more source
Crystal structure of 2-hydroxy-3-(prop-2-yn-1-yl)naphthalene-1,4-dione
The naphthoquinone unit of the title compound, C13H8O3, is essentially planar, with an r.m.s. deviation of 0.013 Å for the non-H atoms. The essentially linear propargyl group is tilted by ca 113° relative to the naphthoquinone plane.
Isidório Raquel Geralda +3 more
doaj +1 more source

