Results 51 to 60 of about 1,605,420 (342)
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker +7 more
wiley +1 more source
The relevance of the psychometrist category as a professional resource: Training-related issues
Orientation: The professional status of psychometrists places them in a position where they can provide a specialist function independently and their services should therefore be relevant to a variety of settings. Research purpose: The aim was to explore
René van Eeden +2 more
doaj +1 more source
Skeletal age and biological maturity in Japan Professional Soccer League U15 category players
One method of determining a person’s biological maturity involves evaluating their bone maturity. Differences in physical abilities among athletes during the growth period are thought to be strongly influenced by differences in bone maturity. Thus, it is
Ryo Takahara, Shumpei Miyakawa
doaj +1 more source
The Category of "Perception" in the Professional Activity of a Social Worker (Aesthetic Aspect)
The professional activity of a social worker is multifaceted, in which the aesthetic aspect has a special place. The key reason is that it aims to reveal the personality with special needs, the beauty of human existence, its inexhaustible possibilities ...
Hryhoriy Vasianovych +1 more
doaj +1 more source
Work satisfaction within community pharmacy professionals [PDF]
Work is a profession, a craft, or an activity in which man produces something central to his life. The job satisfaction is reflected simultaneously on the worker and the functioning of organizations.
Pinto, Isabel C. +2 more
core
Prevalence of laceration injuries in professional and amateur rugby union: a systematic review and meta-analysis [PDF]
Background: Studded footwear can cause severe lacerations in rugby union; the prevalence of these injuries is currently unknown. Objective: To summarise the skin and laceration injury prevalence in published epidemiological studies and to investigate ...
Best +30 more
core +1 more source
ABSTRACT Bone tumours present significant challenges for affected patients, as multimodal therapy often leads to prolonged physical limitations. This is particularly critical during childhood and adolescence, as it can negatively impact physiological development and psychosocial resilience.
Jennifer Queisser +5 more
wiley +1 more source
ABSTRACT Introduction Cognitive impairment and exercise intolerance are common in dialysis patients. Cerebral perfusion and oxygenation play a major role in both cognitive function and exercise execution; HD session per se aggravates cerebral ischemia in this population. This study aimed to compare cerebral oxygenation and perfusion at rest and in mild
Marieta P. Theodorakopoulou +10 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source

