This study has characterized a functionally distinct macrophage subset, termed CCL5hi macrophages, and elucidated the underlying mechanisms of a regulatory feedback loop that interconnects IFN‐γ, CCL5hi macrophages, and CD8+ T cells within the TME of ESCC undergoing immunochemotherapy.
Yuanzhen Ma +10 more
wiley +1 more source
Perceived abusive supervision and mental health among Chinese graduate students: the chain mediating roles of autonomy need and professional identity. [PDF]
Yao Y, Chen J, Chi H, Hang Y, Qiao Z.
europepmc +1 more source
Teaching identity and professional teaching: concepts and (im)possibilities [PDF]
José Carlos Morgado
openalex
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian +26 more
wiley +1 more source
The impact of creative anxiety on professional identity among master's nursing students: a chain mediation effect of psychological resilience and achievement motivation. [PDF]
Ding Y +5 more
europepmc +1 more source
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian +15 more
wiley +1 more source
Best Practices for Supporting Professional Identity Formation during Laboratory Animal Medicine Residency Training. [PDF]
Nowland MH +3 more
europepmc +1 more source
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang +9 more
wiley +1 more source
Learning Engagement and Professional Identity Among Pre-Service Teachers: The Sequential Mediating Role of Adaptability and Self-Concept. [PDF]
Ye X, Cheng T, Yang W.
europepmc +1 more source
Predicting Immunotherapy Outcomes in NSCLC Using RNA and Pathology from Multicenter Clinical Trials
LIRA, a machine learning‐based model, is developed using transcriptomic data from 891 NSCLC patients in the OAK and POPLAR cohorts. Its predictive performance is validated in multiple external cohorts. Patients stratified by LIRA‐score exhibit distinct clinical characteristics and tumor microenvironment profiles.
Zhaojun Wang +32 more
wiley +1 more source

