Results 121 to 130 of about 35,863 (307)
APPLICATION OF PHARMACOTHERAPY PRINCIPLES IN CHRONIC KIDNEY DISEASE PATIENTS
Chronic renal disease is a kidney illness marked by a progressive decline in kidney function over months or years. The usage of medications in this condition is a crucial aspect of managing kidney disease patients.
Juniarto Mende +3 more
doaj +1 more source
CONTENT OF THE PROFESSIONAL EDUCATIONAL PROGRAM «PEDAGOGICAL CONSULTING» TRAINING MASTERS SPECIALTY 011 EDUCATIONAL, PEDAGOGICAL SCIENCES [PDF]
Valentyna Saiuk
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In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt +14 more
wiley +1 more source
The OBJN upgrade: now it is the official journal of the professional master in nursing program at the Fluminense Federal University Nursing School! [PDF]
Isabel Cristina Fonseca da Cruz
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Engineering MnPt Bimetallic Nanozymes for Cascade Enzymatic Therapy and Enhanced Radio‐Immunotherapy
A CD44‐targeted MnPt bimetallic nanozyme (HD@MnO2) integrates multienzyme‐like activity with cGAS–STING activation to boost radio‐immunotherapy. Through cascade biocatalysis, it depletes glutathione, relieves hypoxia, and amplifies ROS, enhancing radiotherapy‐induced DNA damage and immunogenic cell death. The nanozyme promotes dendritic cell maturation
Wenyi Zhang +8 more
wiley +1 more source
Diabetes is an independent risk factor for gallstones. It upregulates CXCR2 expression in hepatic neutrophils, stimulating the formation of NETs that disrupt hepatocellular tight junctions and the liver‐bile barrier. NETs enter bile to accelerate gallstone development, while sarcosine inhibits CXCR2 and NETs production, effectively reducing diabetes ...
Chao Shi +10 more
wiley +1 more source
Evaluation of the Professional Science Masters (PSM) Degree for Mechanical Engineering Technology Programs [PDF]
David J. Kukulka, James Mayrose
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Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao +8 more
wiley +1 more source
The engineered TF‐Fe@LC nanoplatform programs paraptotic death via multipath ROS amplification that disrupts redox homeostasis, provoking mitochondrial dysfunction, autophagic blockade, and ER stress. This caspase‐independent process elicits robust immunogenic cell death, combining with αPD‐L1 to activate systemic CD8+ T‐cell immunity and suppress ...
Zhe Yu +9 more
wiley +1 more source

