Results 121 to 130 of about 744,615 (290)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
The Economics of Language: An Introduction and Overview [PDF]
This paper provides an introduction and overview of my research on the Economics of Language. The approach is that language skills among immigrants and native-born linguistic minorities are a form of human capital. There are costs and benefits associated
Chiswick, Barry R.
core
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Factors in Students’ Errors in English Writing Proficiency
Namibian Journal of Linguistics, Literature and Communication StudiesEnglish is the sole medium of instruction in Namibian higher education institutions. The fact that more than 90% of Namibian students do not speak English as their home language has often been indicated as the cause of students’ poor performance in ...
Penehafo Henok +1 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Embedding L2 Proficiency Pedagogy into ESOL Teacher Education
TESOL TodayThis article considers an exploratory study designed to understand the relevancy of a course unit on L2 proficiency to pre-service ESOL teachers’ understanding of the nature of the concept of proficiency and their awareness of strategies for developing ...
Brian Hibbs
doaj +1 more source
Bilingualism: Language and CognitionAbstract We investigated which objective language proficiency tests best predict the language dominance, balance, English and Spanish proficiency scores relative to Oral Proficiency Interview (OPI) scores (averaged across 5–6 raters). Eighty Spanish–English bilinguals completed OPIs, picture naming, semantic and letter fluency, lexical decision ...
Anne Neveu +6 more
openaire +1 more source
Isolated learners from diverse language backgrounds in the mainstream primary classroom: A sociocultural perspective [PDF]
, 2005 This paper focuses on the linguistic and cultural (‘languaculture’, Agar, 1994) challenges faced by learners from diverse language backgrounds (DLB) in New Zealand schools.
Barnard, Roger
core +1 more source