Results 121 to 130 of about 738,058 (288)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Isolated learners from diverse language backgrounds in the mainstream primary classroom: A sociocultural perspective [PDF]

open access: yes, 2005
This paper focuses on the linguistic and cultural (‘languaculture’, Agar, 1994) challenges faced by learners from diverse language backgrounds (DLB) in New Zealand schools.
Barnard, Roger
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Embedding L2 Proficiency Pedagogy into ESOL Teacher Education

open access: yesTESOL Today
This article considers an exploratory study designed to understand the relevancy of a course unit on L2 proficiency to pre-service ESOL teachers’ understanding of the nature of the concept of proficiency and their awareness of strategies for developing ...
Brian Hibbs
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nurse-Patient Communication: An Examination of Student-Nurses of Post Basic Nursing Anesthesia (PBNA) and Peri-Operative Nursing (PON) of Jos University Teaching Hospital (JUTH), Plateau State, Nigeria

open access: yesJournal of Literature and Education
Effective nurse-patient communication is essential for providing high-quality healthcare and ensuring patient safety and satisfaction. Proficiency in English is crucial for nurses to effectively interact with patients, families, and other healthcare ...
Patricia Nathan Bwai   +1 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Recent scientific findings on the professional formation of technology teacher

open access: yesJournal of Education, Health and Sport, 2016
The article reviews the latest scientific findings on the professional formation of technology teacher. It analyzes major approaches towards the models of major proficiency levelsand defines the notion of “professional identity of technology teacher”.
Ihor Hevko
doaj  

Proficiency [PDF]

open access: yesBusiness Communication Quarterly, 2004
openaire   +1 more source

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