Results 111 to 120 of about 14,176,450 (371)
Introduction: Forensic Fail [PDF]
, 2014 Background: About 60% of Pheochromocytoma (PCC) and Paraganglioma (PGL) patients have either germline or somatic mutations in one of the 12 proposed disease causing genes; SDHA, SDHB, SDHC, SDHD, SDHAF2, VHL, EPAS1, RET, NF1, TMEM127, MAX and H-RAS ...
Björklund, Peyman +6 more
core +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Blood Alcohol Proficiency Testing Scheme 2009
Journal of Associated Medical Sciences, 2010 Blood Alcohol Proficiency Testing Scheme was performed as a part of Medical Sciences Proficiency Testing Program. The inter-laboratory comparison was established among twenty four member laboratories throughout Thailand.
Jirapun Bunsoong, Thamarat Bunsoong
doaj
High School End-of-Course Exams Show Proficiency Gains for 2010 [PDF]
, 2010 In July, the ADE released results for the 2009-10 end-ofcourse (EOC) exams given in Algebra I, Geometry, and Biology administered in April 2010. These results followed the Grade 11 Literacy results released in June.
Jensen, Nathan C., Ritter, Gary W.
core +2 more sources
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The fifth international radiocarbon intercomparison (VIRI): An assessment of laboratory performance in stage 3 [PDF]
, 2010 Proficiency testing is a widely used, international procedure common within the analytical chemistry community. A proficiency trial (which VIRI is) often follows a standard protocol, including analysis that is typically based on zscores, with one key ...
Cook, G., Naysmith, P., Scott, E.M.
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
EviPlant: An efficient digital forensic challenge creation, manipulation and distribution solution
, 2017 Education and training in digital forensics requires a variety of suitable challenge corpora containing realistic features including regular wear-and-tear, background noise, and the actual digital traces to be discovered during investigation.
Du, Xiaoyu, Lillis, David, Scanlon, Mark
core +1 more source