Preparation of acid-fast microscopy smears for proficiency testing and quality control [PDF]
R W Smithwick, C B Stratigos
openalex +1 more source
Data Analysis for Proficiency Testing
Proficiency Testing (PT) determines the performance of individual laboratories for specific tests or measurements and it is used to monitor the reliability of laboratories measurements. PT plays a highly valuable role as it provides an objective evidence of the competence of the participant laboratories.
Aoki, Reiko +3 more
openaire +2 more sources
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
Participation in proficiency testing is not only an obligation for all analytical laboratories which tend to be credible, but also an opportunity to check how the results agree with the reference or assign value.
Nataša Mikulec +5 more
doaj
The use of a technical questionnaire in laboratory proficiency testing. [PDF]
Ron Neimeister +4 more
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Integration of multimedia technology into the curriculum of forensic science courses using crime scene investigations. [PDF]
Virtual reality technology is a powerful tool for the development of experimental learning in practical situations. Creation of software packages with some element of virtual learning allows educators to broaden the available experience of students ...
Hammerton, Matthew +2 more
core +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source
Interlaboratory proficiency-testing programs: a computer model to assess their capability to correctly characterize intralaboratory performance. [PDF]
Sharon S. Ehrmeyer, Ronald H. Laessig
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Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner +6 more
wiley +1 more source

