Results 151 to 160 of about 64,429 (261)

Longitudinal Evaluation of AFP and CEA External Proficiency Testing Reveals Need for Method Harmonization. [PDF]

Diagnostics (Basel), 2023
Wojtalewicz N, Vierbaum L, Kaufmann A, Schellenberg I, Holdenrieder S.   +4 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Proficiency testing for urinary iodine and its impact on laboratory research related to iodine deficiency disorders (IDD) in the central Africa subregion. [PDF]

Thyroid Res
Bonglaisin JN, Wangue SMK, Yenika FL, Manet L, Kamini MG, Tata BN, Nkeunen G, Sakava P, Matchawe C, Medoua GN.   +9 more
europepmc   +1 more source

Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy

Molecular Oncology, EarlyView.
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir, Elena Haro‐Martínez, Sandra Blasco‐Benito, Chiara Cannatà, José Ángel Palomeque, Anna López‐Plana, Maria Sanz‐Flores, Marc Sabartés, Cristina Fornaguera, Toni Celià‐Terrassa   +9 more
wiley   +1 more source

Five-Year Experience of the Groupe de Recherche Action en Santé (GRAS) Clinical Laboratory, Burkina Faso, in Participating into an External Proficiency Testing (EPT) Programme. [PDF]

Diagnostics (Basel)
Diarra A, Nébié I, Henry NB, Ouédraogo A, Konaté AT, Tiono AB, Sirima SB.   +6 more
europepmc   +1 more source

Ultrastructural calibration model for proficiency testing. [PDF]

J Appl Stat, 2023
Aoki R, Leão D, Bustamante JPM, Vilca F.   +3 more
europepmc   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

Molecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan, Beatriz Martín‐Gracia, Eva Bassols‐Citores, Krizia Sagini, Maria K. Andersen, Tuula A. Nyman, May‐Britt Tessem, Morten B. Rye, Alicia Llorente   +8 more
wiley   +1 more source

Implementation of a blood proficiency testing scheme for bacterial screening of platelet components. [PDF]

Vox Sang
Prax M, Debes L, Chudy M, Filomena A, Pisani G, Pupella S, Riley M, Sondag-Thull D, Hecquet ML, Emery MP, Pflieger M, Arnould P.   +11 more
europepmc   +1 more source

Results From a Proficiency Testing Pilot for Immunosuppressant Microsampling Assays. [PDF]

Ther Drug Monit, 2023
Veenhof H, Koster RA, Junier LAT, Zweipfenning P, Touw DJ.   +4 more
europepmc   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source