Results 211 to 220 of about 59,390 (261)

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Low utilization of epidemiological cutoff values to interpret <i>in vitro</i> antifungal susceptibility testing among clinical laboratory participants in two College of American Pathologists (CAP) proficiency testing programs. [PDF]

J Clin Microbiol
Sullivan KV, Long T, Hillesland E, Rhoads DD, Wojewoda CM, Zhang SX.   +5 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Proficiency testing of diagnosis in histopathology and immunohistochemistry of breast pathology in China: results from a pilot work of National Single Disease Quality Control Program for breast cancer. [PDF]

BMC Cancer
Xue X, Guo L, Guo C, Li L, Yang L, Wang X, Rao W, Yuan P, Mu J, Li J, Wang B, Zhou Q, Yang W, Liu Y, Xue W, Jia R, Yang W, Ying J.   +17 more
europepmc   +1 more source

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Proficiency testing in agriculture

Veterinary Record, 1977
The development and organisation of proficiency testing in agriculture in England and Wales is described. The National Proficiency Tests Council, which was established as an independent examining body in 1971, is responsible for administering the proficiency testing scheme at a national level.
M, Hinton, P C, Sheppy
openaire   +2 more sources

Proficiency testing of sampling

Analytical Methods, 2017
Proficiency testing of analytical laboratories is now ubiquitous-laboratories need to participate regularly to receive accreditation. The outcome helps participants to detect unexpected sources of uncertainty. But sampling, as well as analysis per se, introduces its own uncertainty in most types of analysis.
openaire   +2 more sources

Proficiency testing of radioimmunoassay

Clinical Biochemistry, 1976
1. Quality control is essential during the setting up and routine application of radioimmunoassay. 2. Aspects discussed include the 50% binding intercept, slope of standard curve, and inter- and intra-assay variance.
openaire   +2 more sources