Results 81 to 90 of about 618,923 (261)
Atmospheric and Oceanic Science Letters, 2019 It is important to be able to characterize the thermal conditions over the equatorial Indian Ocean for both weather forecasting and climate prediction.
Lei WANG +6 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
RESEARCH ON THE FATIGUE PERFORMANCE OF HELICAL GEAR PAIR BASED ON LOAD SPECTRUM
Jixie qiangdu, 2017 The 3D contact finite element model of helical gear pair is built to generate mode neutral file by ANSYS,the flexible dynamics simulation anslysis is carried out by using ADAMS,and contact force of helical gear pair is obtained as load spectrum.
ZHANG YanJie +2 more
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Trudy Odesskogo Politehničeskogo Universiteta, 2022 The object of this study is virtual measuring systems for shape deviation parameters. The article describes the designed virtual instrument for simulating the process of determining the parameters of the shape deviation of cylindrical shafts.
Геннадiй Олександрович Оборський +4 more
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Key Technologies of Machine Vision for Precision Measuring of Profile Deviations
Jixie chuandong, 2019 In this paper novel measuring methods for profile deviation are proposed based on machine vision. After the tangent point of the basic circle and the normal line of the tooth profile through a sampled point are obtained， angles of vectors determining by ...
Dongyuan Ge +5 more
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Applied SciencesIn recent years, paradigms like production quality or zero-defect manufacturing have emerged, highlighting the need to improve quality and reduce waste in manufacturing systems.
Sergio Benavent-Nácher +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source