Results 61 to 70 of about 25,598 (261)
Advanced Science, EarlyView.Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han +20 more
wiley +1 more source
Gear grinding system adapting to higher CNC grinder throughput
MATEC Web of Conferences, 2018 The paper is devoted to a solving an important scientific and technical problem of increasing the productivity of defect-free profile gear grinding on CNC machines on the basis of development of on-machine intelligent subsystems for the grinding ...
Larshin Vasily, Lishchenko Natalya
doaj +1 more source
Towards Understanding Subsurface Characteristics in Burn Process of Gear Profile Grinding. [PDF]
Materials (Basel), 2023 Wen J, Tang J, Shao W, Zhou W, Huang W.
europepmc +1 more source
Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants
Advanced Science, EarlyView.The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann +11 more
wiley +1 more source
Review on the Research of Polishing Technologies for Gear Tooth Profiles
Jixie chuandong, 2023 Gears are the most widely used transmission parts in the modern mechanical transmission system. The precision and surface quality of gear tooth profiles have great influence on the precision, smoothness, reliability and noise of gear transmission.
Chen Yangjian +4 more
doaj
Advanced Science, EarlyView.This review critically examines thermal transport and radiative properties of ultra‐high temperature ceramics for hypersonic flight, advanced nuclear systems, and next‐generation energy conversion devices. It explores phonon–photon–electron interactions, microstructural engineering, thermoelectric conversion, and machine learning‐accelerated multiscale
Zhipeng Pei +8 more
wiley +1 more source
Jixie chuandong, 2009 Many reasons influence the precision of the gear in the process of form grinding helical gear. According to the process of grinding, based on both the error of the grinding wheel axial sectional shape and the error of the relative position of grinding ...
张立功, 王军, 邓效忠
doaj
Advanced Science, EarlyView.This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan +10 more
wiley +1 more source
Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy
Advanced Science, EarlyView.ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang +10 more
wiley +1 more source
Hierarchical Twin Networks Enable Exceptional Strength and Fracture Toughness in Titanium
Advanced Science, EarlyView.A commercial‐purity titanium with hierarchical ultrafine twin structures delivers an exceptional combination of fracture toughness (KJIc) of 187 MPa·m1/2 and specific yield strength of 140 MPa·cm3·g−1, in which pre‐engineered high‐density twin boundaries stimulate massive and
Xiao‐Wei Zou +3 more
wiley +1 more source