Results 51 to 60 of about 2,583,946 (296)

Adjusted Versions of Profile Likelihood and Directed Likelihood, and Extended Likelihood

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1994
SUMMARY Several adjusted and invariant versions of profile likelihood and of directed likelihood (short for signed log-likelihood ratio) are discussed. These adjusted versions, which fall into two groups, are closely related to modified profile likelihood and modified directed likelihood.
openaire   +3 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Adjustments of profile likelihood through predictive densities

, 2011
Estimative predictive density, Modified profile likelihood, Nuisance parameter, Predictive pivot, Profile likelihood, Second-order asymptotics,
Alessandra Salvan, Pace L., Luigi Pace, SALVAN, ALESSANDRA, Laura Ventura, VENTURA, LAURA   +5 more
core   +1 more source

Likelihood for statistically equivalent models [PDF]

, 2009
In likelihood inference we usually assume that the model is fixed and then base inference on the corresponding likelihood function. Often, however, the choice of model is rather arbitrary, and there may be other models which fit the data equally well. We
Copas, John B., Shinto Eguchi, Eguchi, Shinto, John Copas   +3 more
core   +1 more source

Uncertainty components in profile likelihood fits

European Physical Journal C: Particles and Fields
When a measurement of a physical quantity is reported, the total uncertainty is usually decomposed into statistical and systematic uncertainties. This decomposition is not only useful for understanding the contributions to the total uncertainty, but is ...
Andrés Pinto, Zhibo Wu, Fabrice Balli, Nicolas Berger, Maarten Boonekamp, Émilien Chapon, Tatsuo Kawamoto, Bogdan Malaescu   +7 more
doaj   +1 more source

Information Bias and Adjusted Profile Likelihoods

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1996
SUMMARY The bias and information bias of the ordinary profile score statistic are both typically of order O(1). Several additive adjustments to the profile score statistic that reduce its bias to order O(n  −1) have been proposed. In certain situations, the information bias of these adjusted profile score statistics is also reduced to ...
DiCiccio, Thomas J., Martin, Michael A., Stern, Steven E., Young, G. Alastair   +3 more
openaire   +2 more sources

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Improving soil moisture profile reconstruction from ground-penetrating radar data: a maximum likelihood ensemble filter approach [PDF]

Hydrology and Earth System Sciences, 2013
The vertical profile of shallow unsaturated zone soil moisture plays a key role in many hydro-meteorological and agricultural applications. We propose a closed-loop data assimilation procedure based on the maximum likelihood ensemble filter algorithm to ...
A. P. Tran, M. Vanclooster, S. Lambot
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source