Results 41 to 50 of about 346,997 (256)

Cover your bases: asymptotic distributions of the profile likelihood ratio when constraining effective field theories in high-energy physics

SciPost Physics Core, 2023
We investigate the asymptotic distribution of the profile likelihood ratio (PLR) when constraining effective field theories (EFTs) and show that Wilks' theorem is often violated, meaning that we should not assume the PLR to follow a $\chi^2$-distribution.
Florian Urs Bernlochner, Daniel C. Fry, Stephen Burns Menary, Eric Persson
doaj   +1 more source

Adjusted Versions of Profile Likelihood and Directed Likelihood, and Extended Likelihood

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1994
SUMMARY Several adjusted and invariant versions of profile likelihood and of directed likelihood (short for signed log-likelihood ratio) are discussed. These adjusted versions, which fall into two groups, are closely related to modified profile likelihood and modified directed likelihood.
openaire   +3 more sources

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Uncertainty components in profile likelihood fits

European Physical Journal C: Particles and Fields
When a measurement of a physical quantity is reported, the total uncertainty is usually decomposed into statistical and systematic uncertainties. This decomposition is not only useful for understanding the contributions to the total uncertainty, but is ...
Andrés Pinto, Zhibo Wu, Fabrice Balli, Nicolas Berger, Maarten Boonekamp, Émilien Chapon, Tatsuo Kawamoto, Bogdan Malaescu   +7 more
doaj   +1 more source

Information Bias and Adjusted Profile Likelihoods

Journal of the Royal Statistical Society Series B: Statistical Methodology, 1996
SUMMARY The bias and information bias of the ordinary profile score statistic are both typically of order O(1). Several additive adjustments to the profile score statistic that reduce its bias to order O(n  −1) have been proposed. In certain situations, the information bias of these adjusted profile score statistics is also reduced to ...
DiCiccio, Thomas J., Martin, Michael A., Stern, Steven E., Young, G. Alastair   +3 more
openaire   +2 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Determination of Neutron Star Radius from Pulse Profile Modeling Using Profile Likelihood

Universe
In recent years, NICER data have been extensively used to determine neutron star masses and radii via pulse profile modeling. Pulse profile modeling is implemented with the X-PSI package, and the best-fit parameters are typically obtained using Bayesian ...
Vyaas Ramakrishnan, Shantanu Desai
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Improving soil moisture profile reconstruction from ground-penetrating radar data: a maximum likelihood ensemble filter approach [PDF]

Hydrology and Earth System Sciences, 2013
The vertical profile of shallow unsaturated zone soil moisture plays a key role in many hydro-meteorological and agricultural applications. We propose a closed-loop data assimilation procedure based on the maximum likelihood ensemble filter algorithm to ...
A. P. Tran, M. Vanclooster, S. Lambot
doaj   +1 more source