Results 101 to 110 of about 333,801 (297)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

To profile or to marginalize - A SMEFT case study

SciPost Physics
Global SMEFT analyses have become a key interpretation framework for LHC physics, quantifying how well a large set of kinematic measurements agrees with the Standard Model. This agreement is encoded in measured Wilson coefficients and their uncertainties.
Ilaria Brivio, Sebastian Bruggisser, Nina Elmer, Emma Geoffray, Michel Luchmann, Tilman Plehn
doaj   +1 more source

Estimated parameters versus the profile likelihood function for Pakistan.

, 2022
(a), (b), and (c) show the graphs of estimated parameters versus the profile likelihood function for the first, second, and third waves, respectively.
Masud M. A. (13570175), Wasim Abbas (394354), Sajida Parveen (4674337), Anna Park (1831723), Sangil Kim (2225599)   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Parameter Estimation in Semi-Linear Models Using a Maximal Invariant Likelihood Function [PDF]

In this paper, we consider the problem of estimation of semi-linear regression models. Using invariance arguments, Bhowmik and King (2001) have derived the probability density functions of the maximal invariant statistic for the nonlinear component of ...
Jahar L. Bhowmik, Maxwell L. King
core  

a short word on profile likelihood

Freakonometrics, 2012
Profile likelihood is an interesting theory to visualize and compute confidence interval for estimators (see e.g. Venzon & Moolgavkar (1988)). As we will use is, we will plot But more generally, it is possible to consider where .
Arthur Charpentier
openaire   +3 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Classifying Job Value Profiles and Employment Outcomes Among Culinary Arts Graduates

Societies
The job values of college graduates are rapidly changing, but a mismatch between industry expectations and young chefs’ values has emerged. To capture the heterogeneity in job values that traditional variable-centered approaches may overlook, this study ...
Tae-Kyun Na, Saem Han
doaj   +1 more source

Data on likelihood ratios of two-person DNA mixtures interpreted using semi- and fully continuous systems

Data in Brief, 2019
In the paper, “Probabilistic approaches to interpreting two-person DNA mixtures from post-coital specimens” [1], we analysed 102 two-person DNA samples from simulated mixtures and male-female and male-male post-coital specimens.
Jae Joseph Russell B. Rodriguez, Jo-Anne Bright, Jazelyn M. Salvador, Rita P. Laude, Maria Corazon A. De Ungria   +4 more
doaj   +1 more source

Experimental scatter of the fatigue response of additively manufactured components: a statistical method based on the Profile Likelihood. [PDF]

Sci Rep, 2023
Tridello A, Boursier Niutta C, Rossetto M, Berto F, Paolino DS.   +4 more
europepmc   +1 more source