Results 91 to 100 of about 2,583,946 (296)

A novel efficient estimator for three‐dimensional bearings‐only source localisation with unknown sensor altitude and systematic measurement errors

open access: yesIET Radar, Sonar & Navigation
A novel two‐stage profile maximum likelihood estimator is proposed to estimate the source location and the systematic errors jointly, with the aim of addressing the problem of source localisation using angle‐only measurements from a single sensor with ...
Heng‐Yu Hu   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

A Profile Likelihood Theory for the Correlated Gamma-Frailty Model with Current Status Family Data

open access: yes, 2011
99學年度溫啟仲教師升等參考著作A profile likelihood inference is made for the regression coefficient and frailty parameters in the correlated gamma-frailty model for current status family data. With the introduction of an identifiability assumption, the identifiability
Chang, I-shou; Wen, Chi-chung; Wu, Yuh-jenn
core  

Adjustements of the profile likelihood from a new perspective. [PDF]

open access: yes, 2003
Various modifications of the profile likelihood have been proposed over the past twenty years. Their main theoretical basis is higher-order approximation of some target likelihood, defined by a suitable model reduction via conditioning or marginalisation,
Salvan , Alessandra   +2 more
core  

Censored median regression and profile empirical likelihood

open access: yes, 2007
We implement profile empirical likelihood-based inference for censored median regression models. Inference for any specified subvector is carried out by profiling out the nuisance parameters from the plug-in empirical likelihood ratio function proposed
Subramanian, Sundarraman
core   +1 more source

To profile or to marginalize - A SMEFT case study

open access: yesSciPost Physics
Global SMEFT analyses have become a key interpretation framework for LHC physics, quantifying how well a large set of kinematic measurements agrees with the Standard Model. This agreement is encoded in measured Wilson coefficients and their uncertainties.
Ilaria Brivio, Sebastian Bruggisser, Nina Elmer, Emma Geoffray, Michel Luchmann, Tilman Plehn
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Parameter Estimation in Semi-Linear Models Using a Maximal Invariant Likelihood Function [PDF]

open access: yes
In this paper, we consider the problem of estimation of semi-linear regression models. Using invariance arguments, Bhowmik and King (2001) have derived the probability density functions of the maximal invariant statistic for the nonlinear component of ...
Jahar L. Bhowmik, Maxwell L. King
core  

Classifying Job Value Profiles and Employment Outcomes Among Culinary Arts Graduates

open access: yesSocieties
The job values of college graduates are rapidly changing, but a mismatch between industry expectations and young chefs’ values has emerged. To capture the heterogeneity in job values that traditional variable-centered approaches may overlook, this study ...
Tae-Kyun Na, Saem Han
doaj   +1 more source

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