Results 171 to 180 of about 1,311,331 (302)

Novel Hertz Contact Intravascular Lithotripsy: Could We Achieve More in Balloon-Based Calcium Modification? [PDF]

J Clin Med
Mitsis A, Khattab E, Didagelos M, Theodoropoulos KC, Mavrogianni AD, Ziakas A, Fragakis N, Kassimis G.   +7 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Screening of M6a methylated genes associated with preovulatory follicle development in Bashang long-tailed chicken. [PDF]

Poult Sci
Duan X, Xie J, Yin S, Zhang L, Liu Y.
europepmc   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Bulk and Surface Dual-Modification for Stabilizing RuO₂ Anode in 2 A cm^-2 PEMWE Operation. [PDF]

Adv Mater
Tang J, Fang Z, Huang YC, Guan D, Chen B, Shao Z.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

ANALYSIS OF TOоTH PROFILE AND MESHING CHARACTERISTICS OF DOUBLE CYCLOID PIN GEAR TRANSMISSION

Jixie qiangdu
The double cycloid tooth profile was applied to the NN type planetary gear transmission with small tooth difference. By analyzing the concavity, curvature and radius of curvature of the inner and outer cycloid tooth profile, the characteristics of the ...
CUI JianKun, DING JiaLe, SHI YuHeng, ZHANG DeQi   +3 more
doaj  

Visceral segment interrupted constraining suture in physician-modified endografts for dissecting thoracoabdominal aortic aneurysms. [PDF]

J Vasc Surg Cases Innov Tech
Hashizume K, Mori M, Yamazaki M, Yagami T, Haida H, Shimizu H.   +5 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Addressing biases and limitations in feature attribution for circRNA modification profiling. [PDF]

Brief Bioinform
Oka S, Takemura K, Takefuji Y.
europepmc   +1 more source