Results 11 to 20 of about 1,311,331 (302)
Proteome‐Wide Profiling of Readers for DNA Modification [PDF]
Advanced Science, 2021 AbstractDNA modifications, represented by 5‐methylcytosine (5mC), 5‐hydroxymethylcytosine (5hmC), 5‐formylcytosine (5fC), and 5‐carboxylcytosine (5caC), play important roles in epigenetic regulation of biological processes. The specific recognition of DNA modifications by the transcriptional protein machinery is thought to be a potential mechanism for ...
Lin Bai +13 more
openaire +3 more sources
The Profile and Dynamics of RNA Modifications in Animals [PDF]
ChemBioChem, 2017 AbstractMore than a hundred distinct modified nucleosides have been identified in RNA, but little is known about their distribution across different organisms, their dynamic nature and their response to cellular and environmental stress. Mass‐spectrometry‐based methods have been at the forefront of identifying and quantifying modified nucleosides ...
Pieter van Delft +8 more
openaire +5 more sources
Insights into Structural Modifications of Valproic Acid and Their Pharmacological Profile [PDF]
Molecules, 2021 Valproic acid (VPA) is a well-established anticonvulsant drug discovered serendipitously and marketed for the treatment of epilepsy, migraine, bipolar disorder and neuropathic pain. Apart from this, VPA has potential therapeutic applications in other central nervous system (CNS) disorders and in various cancer types.
Manish Kumar Mishra +9 more
openaire +3 more sources
Chemoproteomic Profiling of Phosphoaspartate Modifications in Prokaryotes [PDF]
Angewandte Chemie, 2018 AbstractPhosphorylation at aspartic acid residues represents an abundant and critical post‐translational modification (PTM) in prokaryotes. In contrast to most characterized PTMs, such as phosphorylation at serine or threonine, the phosphoaspartate moiety is intrinsically labile, and therefore incompatible with common proteomic profiling methods ...
Jae Won Chang +3 more
openaire +2 more sources
Modification profiles of bacterial genomes
Nucleic Acids Research, 1982 DNAs were prepared from twenty-six bacterial species and digested with a variety of restriction endonucleases to determine what modifications the DNAs carry. Several general conclusions could be made: 1) First, in no instance was the DNA of a restriction enzyme.
J E, Brooks, R J, Roberts
openaire +3 more sources
Bond Modification of Carbon Rovings through Profiling
Materials, 2022 The load-bearing behavior and the performance of composites depends largely on the bond between the individual components. In reinforced concrete construction, the bond mechanisms are very well researched. In the case of carbon and textile reinforced concrete, however, there is still a need for research, especially since there is a greater number of ...
Paul Penzel +9 more
openaire +2 more sources
Modification of the sterol profile in milk through feeding [PDF]
Journal of Dairy Science, 2019 The fortification of milk with phytosterols is an increasingly common practice to enhance the sterol profile and offer consumers potential health benefits. This study investigated whether cattle feed can influence the profile of phytosterols and cholesterol in the milk produced as an alternative to direct fortification of milk.
Modica, Samantha Huynh +8 more
openaire +3 more sources
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2023 Strain wave gear, also known as "harmonic drive" is widely used in the industrial robotics field due to the excellent deceleration performance.
Jianzhong HUANG +4 more
doaj +1 more source
Resolving the plasma profile via differential single inclusive suppression [PDF]
, 2006 The ability of experimental signatures to resolve the spatio-temporal profile of an expanding quark gluon plasma is studied. In particular, the single inclusive suppression of high momentum hadrons versus the centrality of a heavy-ion collision and with ...
A. Majumder +6 more
core +2 more sources
Astrophysical Axion Bounds [PDF]
, 2006 Axion emission by hot and dense plasmas is a new energy-loss channel for stars. Observational consequences include a modification of the solar sound-speed profile, an increase of the solar neutrino flux, a reduction of the helium-burning lifetime of ...
A. Burrows +97 more
core +2 more sources