Results 171 to 180 of about 606,894 (280)

Toxicity Profile of the Oceanic Pufferfish <i>Lagocephalus lagocephalus</i> in the Eastern Atlantic Area. [PDF]

Mar Drugs
Nocchi N, Santana-Mayor Á, Conde-Díaz A, Hernández-Lopez V, Rodríguez Hernández A, Brito A, Díaz-Marrero AR, Fernández JJ.   +7 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Premature ventricular complexes increase with heart rate in patients with mitral valve prolapse. [PDF]

Int J Cardiol Heart Vasc
Bugge C, Five CK, Ahmed T, Skar PMJ, Castrini AI, Ribe M, Hasselberg NE, Dejgaard LA, Stokke MK, Haugaa KH, Aabel EW.   +10 more
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Sedation in Gastrointestinal Endoscopy: From Drug-Centered Protocols to Personalized, Technology-Supported Pathways: A Narrative Review. [PDF]

J Clin Med
Bonura GF, Soriani P, Gualandi N, Cortegoso Valdivia P, Gabbani T, Parrella A, Koulaouzidis A, Manno M.   +7 more
europepmc   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

Dataset of temperature and relative humidity measurements in domestic refrigerators in Bangkok Thailand. [PDF]

Data Brief
Paviet-Salomon Y, Chaomuang N, Potisuwan C, Derens-Bertheau E, Nukunudompanich M, Laguerre O.   +5 more
europepmc   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

An M5Stamp Pico-Based IoT Soil Monitoring System for Soil Water-Salinity Diagnosis in a Coastal Reclaimed Pepper Greenhouse. [PDF]

Sensors (Basel)
Nakayama L, Tokumoto I.
europepmc   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito, Chiara Meneghini, Alice Galli, Luca Gallo, Pierfrancesco Mitrotti, Paola Dimartino, Marianna Inglese, Cinzia Zatti, Alessandro Lupini, Andrea Pilotto, Alessandro Padovani, Micol Avenali, Enza Maria Valente, Cristina Tassorelli, Silvia P. Caminiti   +14 more
wiley   +1 more source