Results 101 to 110 of about 3,277,020 (308)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Generation of synthetic benchmark electrical load profiles using publicly available load and weather data [PDF]

open access: yes, 2014
Electrical load profiles of a particular region are usually required in order to study the performance of renewable energy technologies and the impact of different operational strategies on the power grid. Load profiles are generally constructed based on
Pillai, Gobind   +3 more
core   +1 more source

Comparisons and Comments on Electron and Ion Impact Profiles of Spectral Lines

open access: yesOpen Astronomy, 2011
Stark broadening theory is currently operated for calculating widths and shifts of spectral lines that are needed for spectroscopic diagnostics and modeling in astrophysics, laboratory and technological plasmas. We have calculated a great number of data,
Sahal-Bréchot Sylvie   +2 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Idiographic Momentary Profiles of Personality Facets

open access: yes
Personality psychology has long focused on between-person differences, often neglecting the dynamic, idiographic nature of personality as it unfolds over time.
Emorie Beck, Colin J. Lee
core   +3 more sources

Do Anthropometric Health Risk Indicators of South African Primary School Children Require National Growth Charts? Insights from the NW-CHILD Study

open access: yesChildren
Background/Objectives: Growth monitoring and screening are vital indicators for child wellness. Controversy exists regarding the use of national versus international growth charts for school-going children.
Xonné Muller   +5 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Health behavior profiles and association with mental health status among US active-duty service members

open access: yesFrontiers in Public Health
IntroductionThis study investigated the clustering of health behaviors among US active duty servicemembers (ADSM) into risk profiles and explored the association between these profiles with ADSM sociodemographic characteristics and mental health status ...
Bolanle Olapeju   +5 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

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