Results 91 to 100 of about 5,008,337 (326)

Using Optically Stimulated Luminescence to Unravel Sedimentary Processes of the Usumacinta and Grijalva Rivers (SE Mexico) [PDF]

, 2012
This report provides an optically stimulated luminescence (OSL) chronology for sediment collected through terrace deposits of the Usumacinta and Grijalva rivers in SE Mexico.
Kinnaird, T.K., Munoz-Salinas, E., Sanderson, D.   +2 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Circulating miR‐144‐3p as a Novel Independent Biomarker Associated With Low Muscle Strength Among Older Adults

Journal of Cachexia, Sarcopenia and Muscle
Background Low muscle strength, a key component of sarcopenia, is significant in the development of adverse health outcomes among older adults. MicroRNAs (miRNAs) have been implicated in mechanisms of sarcopenia; however, their specific functions in ...
Hyung Eun Shin, Chang Won Won, Gustavo Duque, Miji Kim   +3 more
doaj   +1 more source

Understand Your Chains: Towards Performance Profile-based Network Service Management

, 2017
Allocating resources to virtualized network functions and services to meet service level agreements is a challenging task for NFV management and orchestration systems.
Karl, Holger, Peuster, Manuel
core   +1 more source

Comment on: “Challenging the Odds: Long‐Term Survival in Pediatric Diffuse Midline Glioma With H3 K27M and BRAF V600 Co‐Mutations Treated With Upfront Radiotherapy and Targeted Therapy”

Pediatric Blood &Cancer, EarlyView.
Natália Dassi, Andrea Maria Cappellano
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Elucidating novel immune profiles for predicting infection in high‐risk cohorts: a pilot study in patients with relapsed and refractory chronic lymphocytic leukaemia

Clinical & Translational Immunology
Objectives Chronic lymphocytic leukaemia (CLL) patients are at increased risk for infection, with the risk even higher for relapsed and refractory patients.
Lewis J Williams, Connie SN Li‐Wai‐Suen, Alex L Garnham, Stefanie M Bader, Constantine S Tam, Ashley Whitechurch, Monica A Slavin, Marcel Doerflinger, Benjamin W Teh   +8 more
doaj   +1 more source

The m6A Dynamics of Profilin in Neurogenesis

Frontiers in Genetics, 2019
Our understanding of the biological role of N6-methyladenosine (m6A), a ubiquitous non-editing RNA modification, has increased greatly since 2011. More recently, work from several labs revealed that m6A methylation regulates several aspects of mRNA ...
Antonio L. Rockwell, Cintia F. Hongay
doaj   +1 more source

Molecular, spatial, and functional single-cell profiling of the hypothalamic preoptic region

Science, 2018
Mapping the brain, one neuron at a time Spatial transcriptomics can link molecularly described cell types to their anatomical positions and functional roles. Moffitt et al.
J. Moffitt, Dhananjay Bambah-Mukku, Stephen W. Eichhorn, Eric Vaughn, K. Shekhar, Julio D. Perez, Nimrod D. Rubinstein, Junjie Hao, A. Regev, C. Dulac, X. Zhuang   +10 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source