Results 131 to 140 of about 5,008,337 (326)
Cancer Management and Research, 2018 Shi Jin,1,* Shoubo Cao,1,2,* Aleksei Grigorev,3,* Jianhua Li,4 Qingwei Meng,1 Chunyan Wang,1,2 Meiyan Feng,5 Jing Hu,1 Feng Jiang,3 Yan Yu1 1Department of Medical Oncology, Harbin Medical University Cancer Hospital, Harbin, People’s Republic of ...
Jin S +9 more
doaj
Data communications and monitor for the Penn State University profiler network [PDF]
, 1986 The profiler network installed by the Department of Meteorology at Penn State University utilizes a microcomputer for network monitoring and control. The network consists of two VHF and one UHF wind profiling Doppler radars.
Peters, R. M.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Digitalization and Labour Market: the Role of Profiling in Occupational Transitions
Italian Labour Law e-JournalThe contribution delves into the digitalization of active labour market policies (ALMPs) and public employment services (PES), with a specific focus on the unemployed profiling procedure, as it represents one of the most sensitive processes to ...
Anna Bebber
doaj +1 more source
Tissue signals imprint ILC2 identity with anticipatory function. [PDF]
, 2018 Group 2 innate lymphoid cells (ILC2s) are distributed systemically and produce type 2 cytokines in response to a variety of stimuli, including the epithelial cytokines interleukin (IL)-25, IL-33, and thymic stromal lymphopoietin (TSLP).
Eckalbar, Walter L +10 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Capturing cross-border continuity: The case of the Czech-Polish borderland
Moravian Geographical Reports, 2019 The differences in welfare amongst European countries are especially evident in border regions, and this affects cross-border cooperation and relationships. Due to the historical development of Central and Eastern European countries over the last century,
Pászto Vít +4 more
doaj +1 more source
Performance characteristics of wind profiling radars [PDF]
, 1986 Doppler radars used to measure winds in the troposphere and lower stratosphere for weather analysis and forecasting are lower-sensitivity versions of mesosphere-stratosphere-troposphere radars widely used for research.
Frisch, A. S. +2 more
core +1 more source