Results 111 to 120 of about 509,325 (277)

Outcome-based pricing for new pharmaceuticals via rebates [PDF]

open access: yes, 2020
The price of new brand-name prescription drugs has been rising fast in the United States. For example, the Amgen cholesterol drug Repatha had an initial list price of $14,523 per year.
Adida, E
core  

Problems on the Making of Mathematical Modelling of a Profit-Loss Sharing Scheme Using Data Simulation

open access: yesJournal of Mathematical and Fundamental Sciences, 2015
The mathematical model for a profit-loss sharing scheme is formulated in order to see how this scheme can replace the traditional practice of lending money against high interest by usurers. It is sourced from the musyarakah method in Islamic Syariah law and implemented for small-scale investments of traditional-market traders.
Novriana Sumarti   +4 more
openaire   +3 more sources

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Determination of Profit and Loss Sharing Ratios in Interest-Free Business Finance [PDF]

open access: yes
This paper discusses how profit and loss sharing ratios will be determined at the micro and micro levels in an interest free system of financing business operating side by side of an interest based conventional financing.It shows that leverage ...
Hasan, Zubair
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Profit and loss Sharing Negotiations involving a VC and an entrepreneur: A Game Theoretic Approach with Agent Based Simulation [abstract only] [PDF]

open access: yes
Profit and Loss Sharing contracts (PLS) are forms of financing where profits are shared according to a predetermined ratio and losses are shared according to each participant’s ratio in the project’s capital.
Elfakir, Adil, Tkiouat, Mohamed
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

open access: yesFEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Analisis Eksternal dan Internal dalam Menentukan Non Performing Financing Bank Umum Syariah di Indonesia [PDF]

open access: yes, 2012
This study aims to examine and analyze the Non Performing Financing of Sharia Banks in Indonesia. Thisresearch is important to do because of bad credit has a very high fluctuation.
Mutamimah, M. (Mutamimah)   +1 more
core  

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