Results 141 to 150 of about 3,212,771 (303)

Development of road transport emission standards

open access: yesProduction Engineering Archives, 2015
Emissions from road vehicles are playing an important role in air quality which has a significant impact on human health. Pollut-ant emissions have to be precisely determined to ensure that air quality plans are designed and realized properly.
Eszter Horvath, Adam Torok
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Access to Microfinance: Does it Matter for Profit Efficiency Among Small Scale Rice Farmers in Bangladesh? [PDF]

open access: yes
This paper measures profit efficiency and examines the effect of access to microfinance on the performance of rice firms in Bangladesh. An extended Cobb-Douglas stochastic frontier profit function was used to assess profit efficiency and profit loss of ...
Islam, K.M. Zahidul   +2 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Hands-On educational model in Nigeria increases interest in STEM careers

open access: yesAnnals of Global Health, 2016
T. Ajayi   +8 more
doaj   +1 more source

Popularity versus quality in TikTok educational videos on congenital nasolacrimal duct obstruction. [PDF]

open access: yesFront Med (Lausanne)
Zhu M   +8 more
europepmc   +1 more source

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