Results 261 to 270 of about 3,821,770 (397)
A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Insights into healthcare public managers' compensation: Influential factors and sustainable financing solutions: A scoping review. [PDF]
Alayi R +3 more
europepmc +1 more source
Profit shifting from Nigeria to Europe: The impact on human rights
Rachel Etter‐Phoya +4 more
openalex +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Omnichannel pricing and inventory strategies considering live streaming selling: A data-driven distributionally robust optimization approach. [PDF]
Mou Y, Zhou H, Yang X, Guan Z.
europepmc +1 more source
Credit risk and Basel II: Are non-profit firms financially different?
Barbara Luppi +2 more
openalex +2 more sources

