Results 51 to 60 of about 359,893 (218)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

WORKLOAD STANDARDS FOR SURGICAL DOCTORS IN HEALTHCARE INSTITUTIONS PROVIDING SPECIALIZED MEDICAL CARE

Acta Medica Leopoliensia
WORKLOAD STANDARDS FOR SURGICAL DOCTORS IN HEALTHCARE INSTITUTIONS PROVIDING SPECIALIZED MEDICAL ...
Orest Chemerys, Orest Sichkoriz, Taras Gutor, Andriy Stasyshyn, Oleh Matviychuk, Taras Kyryk, Yurij Holyk, Dariy Bidyuk, Volodymyr Khomyak, Ihor Trutyak, Oleksandr Shchur, Nazar Kalynovych, Andrii Nakonechnyi, Oleksiy Leoshyk   +13 more
doaj   +1 more source

Methodical Considerations and Resistance Evaluation against F. graminearum and F. culmorum Head Blight in Wheat. The Influence of Mixture of Isolates on Aggressiveness and Resistance Expression

Microorganisms, 2020
In resistance tests to Fusarium head blight (FHB), the mixing of inocula before inoculation is normal, but no information about the background of mixing was given.
Akos Mesterhazy, Andrea Gyorgy, Monika Varga, Beata Toth   +3 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Repetition-rate-independent post-compression to achieve carrier-envelope phase stable few-cycle laser pulses

High Power Laser Science and Engineering
The ELI ERIC facility offers international users ultrashort laser sources via the ALPS facility focusing on few-cycle laser drivers for attosecond pulses, particle beams and ultrahigh intensity interactions.
Barnabás Gilicze, Imre Seres, Zsolt Bengery, Tamás Bartyik, Tamás Csizmadia, Lénárd Gulyás Oldal, Zsolt Kovács, Roland Nagymihaly, Katalin Varjú, Péter Jójárt, Ádám Börzsönyi, Zoltán Várallyay   +11 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Preharvest Natural Multitoxin Contamination of Winter Wheat Genotypes in Hungary with Special Attention to Aflatoxins and HT-2 Toxin

Agriculture
Toxigenic fungi are among the most significant disease-causing agents in wheat. DON is the most common Fusarium mycotoxin, and for a long time, it was the only toxin researched. However, multitoxin data from wheat samples have drawn attention to the fact
Attila Berényi, Balázs Szabó, Tamás Meszlényi, Csaba Vágvölgyi, Beáta Tóth, Ákos Mesterházy   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source