Results 51 to 60 of about 20,515 (247)

SEP: Strategic Engagement and Planning

open access: yes, 2021
Strategic Engagement and Planning (SEP) was formed to work, in a collaborative fashion to increase capacity, improve sustainability, and foster conditions necessary for economic prosperity for the university and the communities we serve.
Strategic Engagement and Planning   +1 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

The fuzzy goal programming approach to production planning of intermediate gear spare parts: a case study

open access: yesJurnal Sistem dan Manajemen Industri, 2020
Production planning has an important role in the company's business processes. A company engaged in the manufacture of intermediate gear parts has a problem in optimizing its production system. The production planning system that occurs is still based on
Aulia Ishak, Poltak Nababan
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

IS PLANNING IN NON-PROFIT ORGANIZATIONS: AN EXPLORATORY STUDY [PDF]

open access: yesIssues in Information Systems, 2003
The amount of textual data that is available for researchers and businesses to analyze is increasing at a dramatic rate. This reality has led IS researchers to investigate various text mining techniques.
Janice Klemz, Gerry Simon, Anil Kumar
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Optimization of Production Planning Using Goal Programming Approach at Chocolate Factory

open access: yesMATEC Web of Conferences, 2018
Company X is a mini chocolate factory in West Sumatera Province. The Company produces three types of product, that is paralin chocolate, bar chocolate 75 gr and bar chocolate 20 gr.
Noviyarsi   +2 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Covid-19 and spatial planning

open access: yesTeMA: Journal of Land Use, Mobility and Environment, 2020
This article analyzes some relevant questions as regards the impact of COVID-19-related social living conditions on spatial planning policies and practices.
Sabrina Lai   +2 more
doaj   +1 more source

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