Results 51 to 60 of about 24,571 (203)

KRT14 Drives Basal Muscle‐Invasive Bladder Cancer Progression and Lung Metastasis by Directly Binding to and Stabilizing IGF2BP1

Advanced Science, EarlyView.
We identified a Krt14+ Igf2bp1+ bladder cancer population linked to EMT. Mechanistically, KRT14 stabilizes and transports IGF2BP1 to invasive protrusions, initiating a positive feedback loop that drives metastasis and poor outcomes. ABSTRACT Basal‐type muscle‐invasive bladder cancer (BMIBC) is characterized by aggressive metastasis and poor prognosis ...
Shirui Huang, Zhihan Zhou, Qipeng Xie, Zheng Wang, Lijiong He, Yutong Liu, Lijuan Huang, Liuxian Ye, Limeng Hu, Baokun Li, Yang Wang, Xiaohui Hua, Xuelei Liu, Yunping Zhao, Jingxia Li, Jinfei Chen, Guiying Wang, Xian Shen, Wei Chen, Chuanshu Huang   +19 more
wiley   +1 more source

VARIABILITY OF MORPHOLOGICAL AND ECONOMIC ALFALFA PROGENIES TRAITS FROM “POLYCROSS” NURSERY [PDF]

Poljoprivreda, 2000
Plant selection in alfalfa “polycross” nursery is based on genotype plant values, that is plant progeny trait values weighed in field trials. Selected plants or progenies may be used as components in “synthetic” cultivar creation, for improved strain ...
Sonja Grljušić
doaj  

Segregation of powdery mildew (Podosphaera leucotricha [Ell. et Ev. /Salm./]) resistance within 54 apple progenies

Horticultural Science, 2004
The occurrence of powdery mildew after heavy spontaneous infections was evaluated on 2,500 apple seedlings of 54 progenies that were derived from crosses made in 1993 and 1994. At the same time, the response to mildew was also assessed on 47 cultivars or
J. Blažek, J. Křelinová, H. Drahošová   +2 more
doaj   +1 more source

Pericentrosomal Redistribution of the Endoplasmic Reticulum Ensures Organelle Symmetric Inheritance and Mitotic Progression

Advanced Science, EarlyView.
Upon mitotic entry, RTN4 relocalizes to the pericentrosomal region, forming a more tubular ER network around centrosomes. CDK1‐mediated phosphorylation of RTN4 increases its interaction with Rab11 GTPase, facilitating dynein‐dependent transport of RTN4 to the pericentrosomal region.
Xiangyu Xu, Yalin Liu, Rongyi Wang, Wenwen Xu, Hao Shi, Ning Huang, Junlin Teng, Jin Meng, Pengli Zheng, Jianguo Chen   +9 more
wiley   +1 more source

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

Advanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo, Yangyang Zhang, Yongcheng Jin, Siwei Deng, Yongqi Chen, Zheng Feng, Hao Wen, Liu Wang, Yilin Li, Fanghong Ou, Yong Shen, Haiming Li, Tianyao Zhou, Xingzhu Ju, Xiaohua Wu   +14 more
wiley   +1 more source

Enraizamento de Perfilhos de Pupunheira (Bactris gasipaes)

Pesquisa Florestal Brasileira, 2010
Objetivou-se, neste trabalho, aprimorar a técnica de manejo e preparo dos perfilhos e verificar o efeito de progênies e substratos no enraizamento de perfilhos de pupunheira (Bactris gasipaes Kunth. var. gasipaes Henderson).
Anderson Luiz Augusto Tracz, Ivar Wendling, Antonio Nascim Kalil Filho, Álvaro Figueredo dos Santos, Marguerite Germanine Ghislaine Quoirin   +4 more
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Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

Advanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu, Xiaoxu Wang, Shun Li, Xuxin Li, Pengfei Du, Yameng Zheng, Lu Liu, Yanyan Zhang, Omri Wurtzel, Guofeng Cheng   +9 more
wiley   +1 more source

POMAR DE SEMENTES POR MUDAS A PARTIR DA SELEÇÃO DENTRO EM TESTE DE PROGÊNIES DE Myracrodruon urundeuva Fr. All.

Revista do Instituto Florestal, 2007
A conservação genética de espécies arbóreas é fundamental para que as futuras gerações possam usufruir os recursos fornecidos atualmente por estas espécies.
Miguel Luiz Menezes Freitas, Alexandre Magno Sebbenn, Antonio Carlos Scatena Zanatto, Eurípedes Moraes   +3 more
doaj   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

Advanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su, Yi Li, Meng Xiao, Dan Guo, David S. Perlin, Erika Shor, Yingchun Xu, Yingxing Li   +7 more
wiley   +1 more source

Volume de Madeira e Ganho Genético de Progênies de Grevílea (Grevillea robusta Cunn.) de Segunda Geração na Região de Londrina, Paraná

Pesquisa Florestal Brasileira, 2011
Em 1993, a Embrapa Florestas importou da Austrália sementes de 20 procedências de grevílea e, em 1994, importou sementes de 126 progênies oriundas de 23 procedências daquele país.
Emerson Gonçalves Martins, Edinelson José Maciel Neves, José Alfredo Sturion, Nicole Duleba   +3 more
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