Results 81 to 90 of about 24,571 (203)

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

T Cell Plasticity in Systemic Lupus Erythematosus Revealed by Large‐Scale T Cell Receptor Repertoire and Transcriptome Studies

Arthritis &Rheumatology, EarlyView.
Objective We aimed to characterize CD4+ T cell plasticity in human systemic lupus erythematosus (SLE) by leveraging T cell receptor (TCR) repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity. Methods We used TCR
Yasuo Nagafuchi, Masahiro Nakano, Kaitlyn A. Lagattuta, Mineto Ota, Hiroaki Hatano, Haruka Takahashi, Takahiro Itamiya, Hajime Inokuchi, Soumya Raychaudhuri, Tomohisa Okamura, Keishi Fujio, Kazuyoshi Ishigaki   +11 more
wiley   +1 more source

Dual‐Scaffold Technique: Autologous Minced Cartilage and Bone Marrow Aspirate Scaffold Combined With Synthetic Collagen Membrane for Cartilage Repair

Arthroscopy Techniques, EarlyView.
Abstract Treating cartilage injuries has long been a complex challenge; however, recent progress has greatly increased the variety of effective therapeutic approaches. The minced autologous matrix‐induced chondrogenesis plus procedure for full‐thickness knee cartilage lesions uses a collagen matrix combined with shaver‐minced cartilage graft and bone ...
Leonardo Ataíde, Moises Cohen, Pedro Debieux, Camila Cohen Kaleka, José Martins Juliano Eustáquio, Lucas Barbosa   +5 more
wiley   +1 more source

Oseltamivir drug‐disease modelling in infants with influenza virus infection

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Oseltamivir is a commonly used neuraminidase inhibitor for treatment of influenza infection, but little data exist regarding concentration‐response relationships. Methods Pharmacokinetic (PK) and viral dynamic data from an earlier NIAID Collaborative Antiviral Study Group trial in paediatric patients with influenza from 0–23 months of age
Kun Wang, David W. Kimberlin, Richard J. Whitley, Edward P. Acosta, For the National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group   +4 more
wiley   +1 more source

Polycationic Peptide Engineering of Phage Endolysins Expands Host Range and Enhances Antibacterial and Antibiofilm Activities Against Bacillus Species

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The exponential rise in antimicrobial resistance has highlighted the urgent need for the development of alternative antibacterial strategies, including phage‐derived and engineered protein agents such as endolysins and artilysins. In this study, we report the rational design, expression, and functional characterization of novel artilysins ...
Farhat Ansari, Tarushi, Vandan Nagar
wiley   +1 more source

Flight of the dragons: a global review of migration in Odonata

Biological Reviews, EarlyView.
ABSTRACT Insects are the most abundant and ecologically important animal migrants. Yet, we know relatively little about the patterns and processes underlying insect migration. Dragonflies (Anisoptera) and damselflies (Zygoptera) comprise the ancient insect order Odonata, whose ancestors were the first organisms to fly on Earth.
Johanna S.U. Hedlund, Myles Menz, Jason W. Chapman, Alexander Hayward   +3 more
wiley   +1 more source

Progênies superiores de soja resistentes ao tipo 3 do nematóide de cisto da soja Soybean superior progenies with resistance to type 3 soybean cyst nematode

Pesquisa Agropecuária Brasileira, 2005
Os objetivos deste trabalho foram selecionar progênies superiores de soja e avaliá-las, em casa de vegetação, quanto à resistência ao nematóide tipo 3 de cisto da soja (Heterodera glycines).
Roberto Carlos de Oliveira, Antonio Orlando Di Mauro, Sandra Helena Unêda-Trevisoli, Jaime Maia dos Santos, João Ademir de Oliveira, Dilermando Perecin, Neylson Eustáquio Arantes   +6 more
doaj  

Variação genética para caracteres quantitativos em população de Gallesia integrifolia (Spreng.) Harms. Genetic variation for quantitative traits in Gallesia integrifolia (Spreng.) Harms. Population. [PDF]

Revista do Instituto Florestal, 2008
Este estudo avaliou a variação genéticapara os caracteres quantitativos crescimento,sobrevivência e forma do fuste em um teste deprogênies de Gallesia integrifolia procedente deAlvorada do Sul (PR), na Estação Experimentalde Luiz Antônio (SP). O teste de
Eurípedes MORAES, Antonio Carlos Scatena ZANATTO, Alexandre Magno SEBBENN, Miguel Luiz Menezes FREITAS, Marcela Aparecida de MORAES   +4 more
doaj  

Revisiting the Latin Vocabulary of Terminologia Histologica: II. Adjectives and Participles

Clinical Anatomy, EarlyView.
ABSTRACT Terminologia Histologica, the international standard nomenclature of human histology and cytology, contains 1093 Latin words that appear to be used as adjectives. Among these, we identified 56 (5%) with a variety of linguistic issues, including typographical or spelling errors, less favored spelling variants, and several unfortunate word ...
Paul E. Neumann, Mélanie Houle, Stephen Russell, Andrea Barta, Katalin Delbó, Katalin Fogarasi, Nicolás E. Ottone, Mariano del Sol   +7 more
wiley   +1 more source