Results 141 to 150 of about 70,278 (291)
Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases
Advanced Science, EarlyView.This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo +5 more
wiley +1 more source
Advanced Science, EarlyView.Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling +17 more
wiley +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Advanced Science, EarlyView.Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Optimizing progeny size and number of crosses under genomic selection: insights into additive and epistatic contributions to long-term genetic gain. [PDF]
Theor Appl Genetda Silva Viana J +2 more
europepmc +1 more source
Advanced Science, EarlyView.CGRP interacts with HMEC‐1 by binding to surface receptors, influencing the downstream FAK/AKT/VEGF signaling pathway, and promoting the secretion of ANGPTL4 from vascular endothelial cells into the bone microenvironment. This, in turn, regulates the differentiation of BMSCs into osteoblasts, thus promoting bone formation. ABSTRACT Bone angiogenesis is
Qiong Lu +9 more
wiley +1 more source
Screening olour mango half-sib progenies for dwarfing, vigour, and climate resilience. [PDF]
Sci RepShukoor A +8 more
europepmc +1 more source
Rapid Design and Fabrication of Body Conformable Surfaces with Kirigami Cutting and Machine Learning
Advanced Science, EarlyView.By integrating the principles of kirigami cutting and data‐driven modeling, this study aims to develop a personalized, rapid, and low‐cost design and fabrication pipeline for creating body‐conformable surfaces around the knee joint. This pipeline presents a balanced trade‐off between conformability performance and cost for personalizing wearables, thus
Jyotshna Bali +3 more
wiley +1 more source
Climate-Resilient F<sub>3</sub> Progenies of <i>Coffea arabica</i>: Agronomic Traits and Antibiosis to <i>Hypothenemus hampei</i>. [PDF]
Plants (Basel)Molina D +4 more
europepmc +1 more source
Advanced Science, EarlyView.We analyzed long‐read genomic sequencing data obtained from 40 inbred mouse strains to produce a large database of structural variants. This dataset captures the major types of structural variants, which includes deletions, insertions, duplications, and inversions.
Wenlong Ren +6 more
wiley +1 more source