Supplementing Single‐Arm Trials with External Control Arms—Evaluation of German Real‐World Data
Clinical Pharmacology &Therapeutics, EarlyView.As single‐arm trials (SATs) are increasingly used in pharmaceutical research, the validity of such study designs needs to be critically assessed. We characterize the feasibility of supplementing SATs with real‐world data (RWD)‐derived external control arms by determining the proportion of SATs on breast cancer and amyotrophic lateral sclerosis (ALS ...
Martin Russek +2 more
wiley +1 more source
Reproductive Medicine and Biology, 2018 Purpose To evaluate the effectiveness of high‐dose progesterone supplementation for women who are undergoing a frozen‐thawed embryo transfer (FET). Methods Among the 2010 FET cycles that were included in the present study, 1188 were 1200 mg/d of vaginal ...
Yihsien Enatsu +6 more
doaj +1 more source
إنتاج مادة 17 ألفا هيدروكسي البروجستيرون على مستوى المخمر المعملي بواسطة فطرة كاننجهاميلا إيكينولاتا [PDF]
, 1985 The mircrobiological transformation of progesterone by a local isolate of Cunninghamella echiiiulata using a laboratory fermentor was studied. Progresterone (10-50 g/1) wetted by Tween 80 was added to 48-hour old culture and the transformation was left ...
El-Kady, Ismail A., Metwali, Mohamed R.
core +1 more source
Drug Testing and Analysis, EarlyView.An LC–MS/MS method was developed and validated to detect 12 synthetic or endogenous hormonal growth promotants commonly utilized in the livestock industry in the United States at low pg/mg concentrations. ABSTRACT Hormonal growth promotants (HGPs) are a class of pharmaceutical agents commonly administered to cattle in the United States to improve ...
Mary Mosburg +7 more
wiley +1 more source
BMC Pregnancy and Childbirth, 2018 Background Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the distribution of maternal serum progesterone in normal pregnancies compared to ...
Chee Wai Ku +5 more
doaj +1 more source
Improving the reproductive performance of the Muturu breed of cattle in Nigeria using modified Ovsynch and progesterone synchronization protocol : a thesis presented in partial fulfilment of the requirement for the degree of Master of Science in Animal Science, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand [PDF]
, 2017 The Ovsynch protocol has been used in cattle to synchronize ovulation and facilitate fixed-time AI (FTAI) but its efficacy has not been evaluated in the Nigerian Muturu breed of B. indicus cattle. The effects of a modified Ovsynch protocol (modified by
Obianwuna, Uchechukwu
core
Progestins Related to Progesterone and Testosterone Elicit Divergent Human Endometrial Transcriptomes and Biofunctions. [PDF]
, 2020 Progestins are widely used for the treatment of gynecologic disorders and alone, or combined with an estrogen, are used as contraceptives. While their potencies, efficacies and side effects vary due to differences in structures, doses and routes of ...
Balayan, Shayna +8 more
core +1 more source
A Case of Autoimmune Progesterone Dermatitis Misdiagnosed as Allergic Contact Dermatitis
Allergy Asthma and Immunology Research, 2011 Autoimmune progesterone dermatitis is a rare autoimmune response to endogenous progesterone that usually occurs in fertile females. Cutaneous or mucosal lesions develop cyclically during the luteal phase of the menstrual cycle when progesterone levels ...
M. Lee +7 more
semanticscholar +1 more source
Drug Testing and Analysis, EarlyView.In highly trained female athletes, haematological and inflammatory biomarkers were found to be independent of menstrual cycle phase, but oral contraceptive use increased transferrin, reticulocyte count and triglycerides and decreased interleukin‐6.
Katia Collomp +12 more
wiley +1 more source
Coincident Frequencies and Relative Phases Among Female-Brain Signals and Progesterone-Estrogen levels [PDF]
arXiv, 2007 Fourier transform has become a basic tool for analyzing biological signals 1,2,3. Mostly a fast Fourier transform is computed for a finite sequence of data sample 4. This is the standard way apparatuses and modern computerized technology provide information, according with their frequency range, of the well known brain signals Delta, Theta, Alpha 1 ...
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