Results 181 to 190 of about 522,321 (423)

Body mass index as a predictive factor for efficacy of adjuvant taxane‐based chemotherapy in early‐stage breast cancer patients: A pooled analysis from adjuvant GEICAM Spanish Breast Cancer Group and TRIO Translational Research in Oncology Group studies

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Body mass index (BMI) potentially influences outcomes among women with early‐stage breast cancer (EBC). Little is known, however, about relationships between BMI and disease prognosis for different adjuvant taxane‐based chemotherapies. Here, the prognostic effect of BMI on disease recurrence was evaluated among EBC patients treated with ...
José A. García‐Saenz   +18 more
wiley   +1 more source

The TESTBREAST journey: Revisiting the importance of early detection by frequent screening of women at high risk of breast cancer

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Women who are at high risk of breast cancer (BC), either because of a BRCA1/2 mutation or family history, require more aggressive screening. Here, the authors report on the clinical characteristics of the high‐risk women who developed BC during the TESTBREAST study. Of the 1108 participants, 124 (16.5%) developed breast cancer. Their median
Layla Andour   +40 more
wiley   +1 more source

Real‐world comparative effectiveness and safety of Pertuzumab in patients with HER2+ metastatic breast cancer: A pan‐Canadian population‐based cohort study

open access: yesInternational Journal of Cancer, EarlyView.
What's New? In Canada, complexities surrounding provincial cancer care and data access challenge the collection of robust multijurisdictional real‐world evidence (RWE) on cancer therapies. RWE, however, can provide critical insight into the safety and effectiveness of novel therapies. Here, for the Canadian Real‐world Evidence for Value of Cancer Drugs
Caroline E. Muñoz   +31 more
wiley   +1 more source

Studies relating to Polyunsaturated Fatty Acid (PUFA) Supplementation and Fertility in Cattle [PDF]

open access: yes, 2007
End of project reportReproductive inefficiency has a significant impact on the economic performance of both dairy and beef herds, particularly in seasonal calving systems. Nutrition plays a fundamental role in reproduction. Furthermore, there is emerging
Childs, Stuart   +3 more
core  

Managing hydrocephalus in patients with leptomeningeal disease: A multicenter retrospective analysis

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Leptomeningeal disease is a highly palliative condition of tumor cell seeding that can cause symptomatic hydrocephalus. This multi‐center retrospective study of patients with leptomeningeal disease‐associated hydrocephalus compared the placement of ventriculoperitoneal shunts and Rickham reservoirs for cerebrospinal fluid drainage.
Obada T. Alhalabi   +19 more
wiley   +1 more source

Comparison of Transcriptional Activation by Corticosteroids of Human MR (Ile-180) and Human MR Haplotype (Ile180Val) [PDF]

open access: yesarXiv
While the classical function of human mineralocorticoid receptor (MR) is to regulate sodium and potassium homeostasis through aldosterone activation of the kidney MR, the MR also is highly expressed in the brain, where the MR is activated by cortisol in response to stress. Here, we report the half-maximal response (EC50) and fold-activation by cortisol,
arxiv  

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev   +3 more
wiley   +1 more source

The Role of Sex Hormones in Inducing Maternal Uterine Remodeling and Vasodilation During Pregnancy [PDF]

open access: yes, 2018
Uterine vascular adaptations such as vessel growth and vasodilation are needed to facilitate the more than 10-fold increase of uteroplacental blood flow (UPBF) during pregnancy.
Glessner-Fischer, Annie D.
core   +1 more source

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