Results 311 to 320 of about 363,488 (344)
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Spinimmunoassay of progesterone
Biochemical and Biophysical Research Communications, 1975Abstract A spin-labeled derivative of progesterone was prepared: 3(progesterone-1111α-hemisuccinyl)-3 methylamino-2,2,5,5, tetramethyl pyrolidine-1-oxyl. A corresponding antibody was produced by inoculating rabbits with progesterone-11α-hemisuccinyl-(bovine serum albumin). These materials were then used in developing a method to measure progesterone.
Robert Wei, Ramona Almirez
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European Journal of Obstetrics & Gynecology and Reproductive Biology, 2001
The role of progesterone (P) in the mechanism of ovulation is controversial at best. The contraceptive application of P was established in rodents in 1936 and with orally absorbed progestogenes was put to human use. There were hints on the proovulatory actions of P administered before the time of ovulation in rats by 1948.
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The role of progesterone (P) in the mechanism of ovulation is controversial at best. The contraceptive application of P was established in rodents in 1936 and with orally absorbed progestogenes was put to human use. There were hints on the proovulatory actions of P administered before the time of ovulation in rats by 1948.
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Novel Mechanisms of Progesterone Antagonists and Progesterone Receptor
Journal of the Society for Gynecologic Investigation, 2000The progesterone receptor (PR), as a member of the nuclear receptor superfamily of ligand-dependent transcription factors, activates gene transcription through binding to specific palindromic progesterone response elements (PRE) in the promoter region of progestin-responsive genes.
Susan A. Leonhardt +2 more
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Progesterone receptor and the mechanism of action of progesterone antagonists
The Journal of Steroid Biochemistry and Molecular Biology, 1995Currently available progesterone antagonists have been suggested to fall into two categories based on differences in how they interact with and inactivate the progesterone receptor (PR). The anti-progestin ZK98299 (Type I) impairs PR association with DNA, while Type II compounds (RU486, ZK112993, ZK98734) promote PR binding to DNA.
Angelo M. DeMarzo +5 more
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Annals of the New York Academy of Sciences, 2005
Abstract: Recent clinical trials in hormone therapy (HT) for women approaching or past menopause have been disappointing. Most women who have been taking conjugated equine estrogens combined with synthetic progestins have been encouraged to stop these supplements because of increased health risks.
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Abstract: Recent clinical trials in hormone therapy (HT) for women approaching or past menopause have been disappointing. Most women who have been taking conjugated equine estrogens combined with synthetic progestins have been encouraged to stop these supplements because of increased health risks.
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Journal of Endocrinology, 1958
SUMMARY The content of progesterone was determined in the peripheral venous blood of cows from the 32nd day of pregnancy until the day before calving. The level ranged from 0·74 to 0·98 μg progesterone/100 ml. plasma throughout the 32nd-256th day period, but thereafter a marked decrease was observed, and on the day before calving the level ...
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SUMMARY The content of progesterone was determined in the peripheral venous blood of cows from the 32nd day of pregnancy until the day before calving. The level ranged from 0·74 to 0·98 μg progesterone/100 ml. plasma throughout the 32nd-256th day period, but thereafter a marked decrease was observed, and on the day before calving the level ...
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The Biochemistry of Progesterone
1964Publisher Summary This chapter focuses on the progress that has been made in the knowledge of certain aspects of the biochemistry of progesterone in the past few years. The chapter discusses the secretion and metabolism of the hormone. The primary biological action of progesterone is on reproductive processes.
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Archives of Pathology & Laboratory Medicine, 2010
M. E. Hammond +31 more
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M. E. Hammond +31 more
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2015
The major target organ of progesterone is the reproductive system. Progesterone, in association with estrogen, is involved in the development and sexual maturation of the reproductive organs and orchestrates the menstrual cycle. Progesterone takes part in all the processes from the preparation of the uterine decidua, myometrium and cervix during the ...
Edi Vaisbuch, Offer Erez, Roberto Romero
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The major target organ of progesterone is the reproductive system. Progesterone, in association with estrogen, is involved in the development and sexual maturation of the reproductive organs and orchestrates the menstrual cycle. Progesterone takes part in all the processes from the preparation of the uterine decidua, myometrium and cervix during the ...
Edi Vaisbuch, Offer Erez, Roberto Romero
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Progesterone antagonists and progesterone receptor modulators: an overview
Steroids, 2003Since the original description of the structure of the antiprogestin, mifepristone, was published, numerous related compounds have been synthesized which may function as progesterone antagonists (PAs) or progesterone receptor modulators (PRMs). The latter are mixed agonists-antagonists.
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