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Progesterone antagonists and progesterone receptor modulators
Expert Opinion on Investigational Drugs, 2003Since the discovery of the antiprogestin RU 486 (mifepristone), other compounds have been synthesised that function as pure progesterone antagonists or progesterone receptor modulators. The latter are mixed agonists-antagonists. Mifepristone is usually used to terminate pregnancy but these compounds have numerous other applications in female healthcare.
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Journal of Steroid Biochemistry, 1979
Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Archives of Pathology & Laboratory Medicine, 2010
M. E. Hammond +31 more
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M. E. Hammond +31 more
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Intradermal progesterone testing for autoimmune progesterone dermatitis
International Journal of Dermatology, 2022Rafey Rehman +3 more
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Progesterone and the progesterone receptor.
The Journal of reproductive medicine, 2001During the 1990s, extensive research has effectively mapped the progesterone receptor-mediated actions of progesterone and has more recently uncovered nonreceptor-mediated effects--the effect of progesterone on uterine sensitivity to oxytocin, for example, involves direct, nongenomic progesterone action on the uterine oxytocin receptor.
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