Results 371 to 380 of about 522,321 (423)
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Archives of Pathology & Laboratory Medicine, 2010
PURPOSE To develop a guideline to improve the accuracy of immunohistochemical (IHC) estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer and the utility of these receptors as predictive markers.
M. E. Hammond +31 more
semanticscholar +1 more source
PURPOSE To develop a guideline to improve the accuracy of immunohistochemical (IHC) estrogen receptor (ER) and progesterone receptor (PgR) testing in breast cancer and the utility of these receptors as predictive markers.
M. E. Hammond +31 more
semanticscholar +1 more source
Progesterone and progesterone receptors in reptiles
General and Comparative Endocrinology, 2002The role of progesterone (P) has been most extensively studied in the female reproductive tissues (ovary, reproductive tract, mammary gland) and in the brain, in which it is an important regulator and modulator in conjunction with estradiol (E). In nonmammalian vertebrate species, less work has been done on P metabolites involved in ovulation.
Ian P. Callard, Noemı́ Custodia-Lora
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Clinical Obstetrics & Gynecology, 2014
Progestogens are a promising treatment in the prevention of spontaneous preterm birth in high-risk women. In women with a prior history of spontaneous preterm delivery and in women with a sonographic shortened cervix, there is considerable evidence supporting a benefit of progestogen therapy in the reduction of preterm delivery.
Lindsay, Maggio, Dwight J, Rouse
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Progestogens are a promising treatment in the prevention of spontaneous preterm birth in high-risk women. In women with a prior history of spontaneous preterm delivery and in women with a sonographic shortened cervix, there is considerable evidence supporting a benefit of progestogen therapy in the reduction of preterm delivery.
Lindsay, Maggio, Dwight J, Rouse
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A radioimmunoassay for progesterone
Steroids, 1972Abstract The need for a simple and fast quantitative method for progesterone with routine laboratory and clinical application motivated the development of a radioimmunoassay. Progesterone antibodies were produced in rabbits by immunization with a bovine serum albumin conjugate of 11α-hydroxyprogesterone hemisuccinate.
R. J. Saldarini +3 more
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Gynecologic Oncology, 1974
Abstract Coordinated estrogen- and progesterone-induced changes regulate biological functions of the endometrium. The uterine deciduoma reaction is used as a model in defining the mechanism of the progesterone-induced endometrial transformations. Uterine progesterone concentrations were determined by radioimmunoassay during three critical periods ...
Walter G. Wiest, B. Ramanath Rao
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Abstract Coordinated estrogen- and progesterone-induced changes regulate biological functions of the endometrium. The uterine deciduoma reaction is used as a model in defining the mechanism of the progesterone-induced endometrial transformations. Uterine progesterone concentrations were determined by radioimmunoassay during three critical periods ...
Walter G. Wiest, B. Ramanath Rao
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The role of progesterone and the progesterone receptor in cancer
Expert Review of Endocrinology & Metabolism, 2017There is an abundance of accumulating data strongly suggesting there is a key role for the progesterone receptor in the molecular events effecting the growth or containment of a variety of cancers. This knowledge should lead to novel new strategies to combat various cancers, including drugs classified as progesterone receptor modulators or monoclonal ...
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Journal of Steroid Biochemistry, 1979
Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Abstract The effect of progesterone (P) treatment on P receptors and on the resultant P concentrations in the cytoplasm and other subcellular fractions was studied. Cytoplasmic P receptors in the uterus of oestrogenized rabbits were reduced by about 60% after 24 h of single injection of P.
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Acta Endocrinologica, 1974
ABSTRACT The radioactive substances obtained from subcellular uterine fractions and from plasma were separated and identified by analytical TLC's, chemical reactions and crystallization to constant activity 5 min, 20 min and 3 h after the injection of [1,2-3H]progesterone into oestradiol-primed castrated Wistar rats.
Heinrich Maass, Dieter Egert
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ABSTRACT The radioactive substances obtained from subcellular uterine fractions and from plasma were separated and identified by analytical TLC's, chemical reactions and crystallization to constant activity 5 min, 20 min and 3 h after the injection of [1,2-3H]progesterone into oestradiol-primed castrated Wistar rats.
Heinrich Maass, Dieter Egert
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Spinimmunoassay of progesterone
Biochemical and Biophysical Research Communications, 1975Abstract A spin-labeled derivative of progesterone was prepared: 3(progesterone-1111α-hemisuccinyl)-3 methylamino-2,2,5,5, tetramethyl pyrolidine-1-oxyl. A corresponding antibody was produced by inoculating rabbits with progesterone-11α-hemisuccinyl-(bovine serum albumin). These materials were then used in developing a method to measure progesterone.
Robert Wei, Ramona Almirez
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Progesterone antagonists and progesterone receptor modulators
Expert Opinion on Investigational Drugs, 2003Since the discovery of the antiprogestin RU 486 (mifepristone), other compounds have been synthesised that function as pure progesterone antagonists or progesterone receptor modulators. The latter are mixed agonists-antagonists. Mifepristone is usually used to terminate pregnancy but these compounds have numerous other applications in female healthcare.
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