Results 151 to 160 of about 2,330 (251)

Intercellular mitochondrial transfer contributes to microenvironmental redirection of cancer cell fate

The FEBS Journal, Volume 292, Issue 9, Page 2306-2322, May 2025.
The mammary microenvironment has been shown to suppress tumor progression by redirecting cancer cells to adopt a normal mammary epithelial progenitor fate in vivo. Here, we test the hypothesis that mitochondrial transfer from mammary epithelial cells to breast cancer cells plays a role in this redirection process.
Julie Sofie Bjerring, Yara Khodour, Emilee Anne Peterson, Patrick Christian Sachs, Robert David Bruno   +4 more
wiley   +1 more source

A decrease in serum dihydrotestosterone levels in 9-year-old Vietnamese children from a dioxin exposure area. [PDF]

Environ Health Prev Med
Nguyen OTP, Honma S, Hoang PD, Van Nguyen K, Le AT, Nakayama SF, Ho MD, Nguyen VH, Van Dao T, Dang ND, Ngo TTM, Van Pham T, Van Ngo T, Van Vo C, Nakagawa H, Kido T.   +15 more
europepmc   +1 more source

Interactions of the maternal microbiome with diet, stress, and infection influence fetal development

The FEBS Journal, Volume 292, Issue 6, Page 1437-1453, March 2025.
External factors such as diet, stress, and infection interact with the trillions of microorganisms that live within us. During the perinatal period, the gut microbiome acts as a unique interface between external factors and the host to influence offspring nervous system, immune system, and metabolic development.
Chloe H Puglisi, Minjeong Kim, Modi Aldhafeeri, Megan Lewandowski, Helen E. Vuong   +4 more
wiley   +1 more source

Mechanisms of Male Reproductive Toxicity of Polybrominated Diphenyl Ethers. [PDF]

Int J Mol Sci, 2022
Arowolo O, Pilsner JR, Sergeyev O, Suvorov A.   +3 more
europepmc   +1 more source

TENT5C functions as a corepressor in the ligand‐bound glucocorticoid receptor and estrogen receptor α complexes

The FEBS Journal, EarlyView.
TENT5C is a suppressor of ERα and GR transcriptional activation. A specific LXXLL motif in TENT5C, absent in the other members of the TENT5 subfamily, mediates a stable interaction with the Ligand Binding Domain of ERα but not with that of GR.
Yin Li, Lalith Perera, Rebecca S. He, Marine Baptissart, Robert M. Petrovich, Marcos Morgan   +5 more
wiley   +1 more source

Triazole-Estradiol Analogs Induce Apoptosis and Inhibit EGFR and Its Downstream Pathways in Triple Negative Breast Cancer. [PDF]

Molecules
Acheampong F, Ostlund T, Hedge E, Laddusaw J, Alotaibi F, Elshaier YAMM, Halaweish F.   +6 more
europepmc   +1 more source

Longitudinal Course of Sex Steroids From Pregnancy to Postpartum.

Endocrinology, 2023
Dukic J, Ehlert U.
europepmc   +1 more source

Comparative evaluation of biased agonists Sarcosine¹ , d-Alanine⁸ -Angiotensin (Ang) II (SD Ang II) and Sarcosine¹ , Isoleucine⁸ -Ang II (SI Ang II) and their radioiodinated congeners binding to rat liver membrane AT₁ receptors. [PDF]

Pharmacol Res Perspect, 2023
Noto NM, Restrepo YM, Pang HW, Stoyell-Conti F, West CA, Speth RC.   +5 more
europepmc   +1 more source

Threonine and tyrosine kinase (TTK) mRNA and protein expression in breast cancer; prognostic significance in the neoadjuvant setting

Histopathology, Volume 86, Issue 6, Page 916-932, May 2025.
This study investigates threonine and tyrosine kinase (TTK) expression in pre‐ and post‐neoadjuvant chemotherapy breast cancer patients. TTK mRNA expression was elevated in breast cancer tissues, predicting reduced survival. Notably, TTK protein expression in neoadjuvant chemotherapy‐treated breast cancer patients was up‐regulated post‐therapy and ...
Abrar Ashi, Aeshah A Awaji, Jacquelyn Bond, Colin A Johnson, Abeer M Shaaban, Sandra M Bell   +5 more
wiley   +1 more source

Impact of Real-life Environmental Exposures on Reproduction: Endocrine-disrupting chemicals, reproductive aging, and menopause. [PDF]

Reproduction
Inman ZC, Flaws JA.
europepmc   +1 more source