BioEssays, EarlyView.The microfluidic Cervix Chip is an in vitro model of the human cervix lined by cervical epithelium interfaced with stromal cells cultured under dynamic flow that represents a new preclinical platform for studying mucosal immunity, host‐microbiome interactions, infections, fertility, and pregnancy health.
Zohreh Izadifar +4 more
wiley +1 more source
Transcriptional Activation of Elephant Shark Mineralocorticoid Receptor by Corticosteroids, Progesterone and Spironolactone [PDF]
arXiv, 2018 We report the analysis of activation by corticosteroids and progesterone of full-length mineralocorticoid receptor (MR) from elephant shark, a cartilaginous fish belonging to the oldest group of jawed vertebrates. Based on their measured activities, aldosterone, cortisol, 11-deoxycorticosterone, corticosterone, 11-deoxcortisol, progesterone and 19 ...
arxiv
Star network non-n-local correlations can resist consistency noises better [PDF]
arXiv, 2023 Imperfections from devices can result in the decay or even vanish of non-n-local correlations as the number of parties n increases in the polygon and linear quantum networks ([Phys. Rev. A 106, 042206 (2022)] and [Phys. Rev. A 107, 032404 (2023)]).
arxiv
Relations of environmental contaminants, algal toxins, and diet with the reproductive success of American alligators on Florida Lakes [PDF]
, 2001 (113 page ...
Arnold, Beverly S. +3 more
core
Synthesis and Biological Evaluation of Bicyclic Pyrazolines with Promising Antimicrobial Activities
ChemMedChem, EarlyView.Continuous flow technology is exploited for the generation of bicyclic pyrazolines via photo‐click reactions. These heterocyclic species contain a valuable 3D scaffold along with a polar succinimide moiety. Subsequent antimicrobial testing reveals that halogenated moieties such as chlorine atoms and trifluoromethoxy groups enhance the potency of these ...
Debora Caviglia +4 more
wiley +1 more source
Nanostructured Immunosensors. Application to the detection of Progesterone [PDF]
Dans European Nano Systems Worshop - ENS 2006, Paris : France
(2006), 2007 A novel nanostructured electrochemical immunsensor for the determination of progesterone is reported. The approach combines the properties of gold nanoparticles with the use of a graphite-Teflon composite electrode matrix, into which gold nanoparticles are incorporated by simple physical inclusion.
arxiv
Enumeration of saturated and unsaturated substituted N-heterocycles [PDF]
arXiv, 2023 Mathematical and computational approaches in chemistry and biochemistry fill a gap in respect to the analysis of the physicochemical features of compounds and their functionality and provide an overview of known as well as yet unknown, but hypothetically possible structures.
arxiv
Assessment of xenoestrogenic exposure by a biomarker approach: application of the E-Screen bioassay to determine estrogenic response of serum extracts [PDF]
, 2003 BACKGROUND: Epidemiological documentation of endocrine disruption is complicated by imprecise exposure assessment, especially when exposures are mixed. Even if the estrogenic activity of all compounds were known, the combined effect of possible additive ...
A Bergman +40 more
core +4 more sources
Clinical Pharmacology &Therapeutics, EarlyView.A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang +6 more
wiley +1 more source
The effect of environmental, physical, and nutritional factors on in vitro fertilisation [PDF]
, 2016 Folliculogenesis, fertilisation and implantation of a human embryo requires unity of many different pathways. The literature review discusses folliculogensis, implantation and the potential affect that endocrine disrupting agents (EDAs) and Vitamin D can
Cunningham, Thomas K.
core