Results 11 to 20 of about 112,193 (222)

Spatial resolution of cellular senescence dynamics in human colorectal liver metastasis

Aging Cell, Volume 22, Issue 7, July 2023., 2023
Two distinct senescent cancer ecosystems located at the opposite pole of epithelial (e) to mesenchymal (m) transition duel in metastasis onset of colorectal cancer, defining the immune landscape and the clinical fate of patients. Abstract Hepatic metastasis is a clinical challenge for colorectal cancer (CRC).
Ombretta Garbarino, Luca Lambroia, Gianluca Basso, Veronica Marrella, Barbara Franceschini, Cristiana Soldani, Fabio Pasqualini, Desiree Giuliano, Guido Costa, Clelia Peano, Davide Barbarossa, Destro Annarita, Andreina Salvati, Luigi Terracciano, Guido Torzilli, Matteo Donadon, Francesca Faggioli   +16 more
wiley   +1 more source

Healthy preterm newborns: Altered innate immunity and impaired monocyte function

European Journal of Immunology, Volume 53, Issue 5, May 2023., 2023
By investigating innate immune features, we observe notable disparities in proportions and functional capabilities of monocytes between preterm and full‐term infants. Preterm infants present a restricted ability to trigger pro‐inflammatory immune responses.
Sara De Biasi, Anita Neroni, Milena Nasi, Domenico Lo Tartaro, Rebecca Borella, Lara Gibellini, Laura Lucaccioni, Emma Bertucci, Licia Lugli, Francesca Miselli, Luca Bedetti, Isabella Neri, Fabrizio Ferrari, Fabio Facchinetti, Alberto Berardi, Andrea Cossarizza   +15 more
wiley   +1 more source

Self‐determination of people with profound intellectual and multiple disabilities

Developmental Medicine &Child Neurology, Volume 65, Issue 1, Page 16-23, January 2023., 2023
Abstract Self‐determination is a human right that people with profound intellectual and multiple disabilities (PIMD) risk not being granted. Exploration of such topics and research in general has traditionally not included people with PIMD as sources of knowledge; rather, the perspective of others has been sought.
Synne Nese Skarsaune
wiley   +1 more source

Long‐term neurodevelopmental outcome of neonates born at term with perinatal haemorrhagic stroke: A population‐based study

Developmental Medicine &Child Neurology, Volume 64, Issue 8, Page 971-978, August 2022., 2022
Abstract Aim To assess the long‐term neurodevelopmental outcome of neonates born at term diagnosed with perinatal haemorrhagic stroke (PHS) and investigate the associations among brain territorial involvement, clinical risk factors, and neurodevelopmental outcomes. Method We conducted a population‐based study enrolling 55 neonates born at term with PHS
Eszter Vojcek, Rózsa Gráf, Anna M. László, Gyula Gyebnar, Istvan Seri   +4 more
wiley   +1 more source

C‐reactive protein : albumin ratio in patients with resectable intrahepatic cholangiocarcinoma

BJS Open, Volume 4, Issue 6, Page 1146-1152, December 2020., 2020
This study showed that a high C‐reactive protein : albumin ratio (CAR) is an independent predictor of poor recurrence‐free survival in patients with intrahepatic cholangiocarcinoma (ICC). The results also suggest that patients with ICC with a high CAR had a more aggressive tumour behaviour, including a larger tumour size, higher frequency of ...
T. Matsumoto, S. Itoh, T. Yoshizumi, T. Kurihara, S. Yoshiya, Y. Mano, K. Takeishi, N. Harada, T. Ikegami, Y. Soejima, H. Baba, M. Mori   +11 more
wiley   +1 more source

Revisão sistemática e meta-análise de estudos de diagnóstico e prognóstico: um tutorial Revisión sistemática y metaanálisis de estudios de diagnóstico y pronóstico: una guía Systematic review and meta-analysis of diagnostic and prognostic studies: a tutorial

Arquivos Brasileiros de Cardiologia, 2009
As revisões sistemáticas com meta-análise de estudos de exames diagnósticos ou de fatores prognósticos são ferramentas de pesquisa ainda em fase de desenvolvimento.
Marcos R. de Sousa, Antonio Luiz P. Ribeiro   +1 more
doaj   +1 more source

Chromosomal abnormalities in myelodysplastic syndrome [PDF]

, 2006
The study of chromosomal abnormalities in myelodysplastic syndrome (MDS) is important for diagnosis, prognosis, classification, follow-up, therapeutic option and for a better understanding of the biology of the disease.
Chauffaille, Maria de Lourdes Lopes Ferrari
core   +2 more sources

Comportamento distinto dos sorotipos do fator reumatoide em avaliação seriada de pacientes com artrite reumatoide inicial Distinct pattern of rheumatoid factor serotypes in serial evaluation of patients with early rheumatoid arthritis

Revista Brasileira de Reumatologia, 2009
INTRODUÇÃO: O fator reumatoide (FR), apesar de suas limitações, ainda é o marcador sorológico mais utilizado para diagnóstico da artrite reumatoide (AR) inicial. Há controvérsias sobre sensibilidade, especificidade, correlação com prognóstico radiológico
Licia Maria Henrique da Mota, Leopoldo Luiz dos Santos Neto, Rufus Burlingame, Ieda Maria Magalhães Laurindo   +3 more
doaj   +1 more source

Notas sobre a vida social da previsão climática: Um estudo do caso do Estado do Ceará [PDF]

, 2004
O presente trabalho é um estudo dos usos sociais das previsões climáticas no Estado do Ceará, Nordeste Brasileiro. Inicialmente textos importantes e de publicação recente em língua inglesa são apresentados e sumarizados.
Taddei, Renzo
core   +2 more sources

Outcome in critically ill cancer patients: past and present Prognóstico de pacientes com câncer criticamente enfermos: passado e presente

Revista Brasileira de Terapia Intensiva, 2008
BACKGROUND AND OBJECTIVES: Until the end of the previous century it remained controversial to admit cancer patients to the ICU for advanced-life-supporting therapy.
Dominique D. Benoit, Pieter O. Depuydt
doaj   +1 more source