Results 131 to 140 of about 3,512,914 (385)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Mortality in ST-segment elevation myocardial infarction patients without standard modifiable risk factors: A race disaggregated analysis

International Journal of Cardiology: Heart & Vasculature, 2022
Background: Individuals who present with STEMI without the standard cardiovascular risk factors (SMuRFs) of diabetes, hypercholesterolemia, hypertension, and smoking, coined SMuRF-less are not uncommon.
Saadiq M. Moledina, Ofer Kobo, Hammad Lakhani, Abhishek Abhishek, Purvi Parwani, Annabelle Santos Volgman, Rachel M. Bond, Muhammad Rashid, Gemma A. Figtree, Mamas A. Mamas   +9 more
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

DETERMINANTS OF ENERGY CONSUMPTION & FUEL BASE SAFETY [PDF]

, 2018
On the base of studying the current situation in the world mining and fuel consumption author make the prognosis of the country’s economic development and involving new conception of mine ...
KICKI, Jerzy
core  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Prognosis of Encephalitis

Pediatric Neurology Briefs, 1991
A population based, controlled follow-up study of the general outcome of 73 children followed for 2 to 12 years after the acute phase of childhood encephalitis is reported from the University of Oulu, Finland.
openaire   +3 more sources

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Characteristics and Influence Factors of Natural Desorption in Coal Bodies from Fukang Mining Area, Xinjiang, China

ACS Omega, 2023
Liang Du, Xuchao Huang, Zhengshuai Wang, Chuanjian Cheng, Kuwanixibieke Maimaitizhuma, Haichao Wang, Zhenzhi Wang, Zhiwei Zeng, Bing Luo, Mengmeng Yang, Zheyuan Ouyang, Wei Dou, Beixi Zhang, Teng Li   +13 more
doaj   +1 more source

Cytological prognosis in cancer of the uterine cervix treated radiologically [PDF]

, 1955
Ruth M. Graham, John B. Graham
openalex   +1 more source

Pediatric Oncology Nurses’ Perceptions of Prognosis-Related Communication [PDF]

, 2019
Background Disclosure of prognosis-related information is an essential aspect of communication with pediatric patients with cancer and their families. The nurse is believed to play an important role in this process, but nurse perceptions and experiences ...
Haglund, Kristin, Newman, Amy Rose, Rodgers, Cheryl C.   +2 more
core   +1 more source