Results 41 to 50 of about 2,513,039 (315)

Sex Differences in Ischemic Stroke Outcomes in Patients With Pulmonary Hypertension

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background The association between systemic hypertension and cerebrovascular disease is well documented. However, the impact of pulmonary hypertension (PH) on acute ischemic stroke outcomes is unknown despite PH being recognized as a risk factor for ...
Tiberiu A. Pana, Dana K. Dawson, Mohamed O. Mohamed, Fiona Murray, David L. Fischman, Michael P. Savage, Mamas A. Mamas, Phyo K. Myint   +7 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Geological Evaluation of In-Situ Pyrolysis Development of Oil-Rich Coal in Tiaohu Mining Area, Santanghu Basin, Xinjiang, China

Energies
The applicability of the in-situ pyrolysis of oil-rich coal is highly dependent on regional geological conditions. In this study, six major geological factors and 19 key parameters influencing the in-situ pyrolysis of oil-rich coal were systematically ...
Guangxiu Jing, Xiangquan Gao, Shuo Feng, Xin Li, Wenfeng Wang, Tianyin Zhang, Chenchen Li   +6 more
doaj   +1 more source

Guided Wave-Convolutional Neural Network Based Fatigue Crack Diagnosis of Aircraft Structures

Sensors, 2019
Fatigue crack diagnosis (FCD) is of great significance for ensuring safe operation, prolonging service time and reducing maintenance cost in aircrafts and many other safety-critical systems.
Liang Xu, Shenfang Yuan, Jian Chen, Yuanqiang Ren   +3 more
doaj   +1 more source

Design of a Large-Scale Piezoelectric Transducer Network Layer and Its Reliability Verification for Space Structures

Sensors, 2020
As an effective structural health monitoring (SHM) technology, the piezoelectric transducer (PZT) and guided wave-based monitoring methods have attracted growing interest in the space field.
Yuanqiang Ren, Jingya Tao, Zhaopeng Xue
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Platelet‐to‐lymphocyte ratio is associated with prognosis in patients with coronavirus disease‐19

Journal of Medical Virology, 2020
Since December 2019, novel coronavirus infected pneumonia emerged in Wuhan city and rapidly spread throughout China. In severe novel coronavirus pneumonia cases, the number of platelets, their dynamic changes during the treatment, platelet‐to‐lymphocyte ...
Rong Qu, Y. Ling, Yi-huizhi Zhang, Li-ya Wei, Xiao Chen, Xu-ran Li, Xuan-yong Liu, Han-Mian Liu, Zhi Guo, H. Ren, Qiang Wang   +10 more
semanticscholar   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Fabrication and Actuation Performance of Selective Laser Melting Additive-Manufactured Active Shape-Memory Alloy Honeycomb Arrays

Actuators, 2022
Shape-memory alloy (SMA) honeycomb arrays have drawn worldwide attention for their potential active applications in smart morphing wings. However, the manufacturing of complex active SMA honeycomb arrays via conventional processes is a difficult task ...
Yuesheng Xu, Lei Qiu, Shenfang Yuan
doaj   +1 more source