Results 281 to 290 of about 2,011,497 (356)

Minor prognostic associations

Cleveland Clinic Journal of Medicine, 1978
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Clinical Features, Prognosis, and Prognostic Factors of Remnant Gastric Cancer Patients Who Received Potentially Curative Gastrectomy. [PDF]

In Vivo
Aoyama T, Cho H, Suematsu H, Hara K.
europepmc   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Prognostic impact of spatial niches in prostate cancer. [PDF]

Sci Rep
Schneider F, Böning SH, Antunes BC, Kaczorowski A, Görtz M, Schütz V, Huber J, Stenzinger A, Hohenfellner M, Duensing S, Duensing A.   +10 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Machine learning-based integration of tumor deposit molecular signatures improves prognostic stratification in colon adenocarcinoma. [PDF]

Int J Colorectal Dis
Wu J, Wu J, Zheng Z, Chen S.
europepmc   +1 more source

A pseudouridine-related prognostic model of colorectal cancer based on single-cell sequencing analysis and transcriptome analysis. [PDF]

Sci Rep
Wang Z, Ma L, Cao J, Lin S, Ma R, Wang J, Lv H, Zhang Z, Jiang T.   +8 more
europepmc   +1 more source

Integrative analysis of EMT-driving genes identifies a prognostic signature and GJB2 as a potential biomarker in glioblastoma. [PDF]

Front Cell Dev Biol
Liu XF, Wang B, Zhou M, Gong D, Zhang JH, He JY, Xiao WT.   +6 more
europepmc   +1 more source