Communicating prognostic uncertainty in potential end-of-life contexts: experiences of family members [PDF]
Background: This article reports on the concept of “communicating prognostic uncertainty” which emerged from a mixed methods survey asking family members to rank their satisfaction in seven domains of hospital end-of-life care. Methods: Open-ended
Gallagher, Romayne, Krawczyk, Marian
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IntroductionTumor mutation burden (TMB) is an emerging biomarker for immunotherapy of hepatocellular carcinoma (HCC), but its value for clinical application has not been fully revealed.Materials and MethodsWe used the Wilcox test to identify the ...
Junyu Huo, Liqun Wu, Yunjin Zang
doaj +1 more source
Establishment and validation of a polygene prognostic model for clear cell renal cell carcinoma
Purpose: To establish an effective prognostic model for patients with clear cell renal cell carcinoma (ccRCC).Methods: We identified four hub differentially expressed genes (DEGs) in Gene Expression Omnibus (GEO) database and verified them in the Cancer ...
Kai Gan +10 more
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Microsatellite instability, KRAS mutations and cellular distribution of TRAIL-receptors in early stage colorectal cancer. [PDF]
Thus, we evaluated the immunofluorescence pattern of TRAIL-receptors and E-cadherin to assess the fraction of membrane-bound TRAIL-receptors in 231 selected patients with early-stage CRC undergoing surgical treatment only.
De Toni, Enrico N. +10 more
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Prognosis and prognostic research: validating a prognostic model
Prognostic models are of little clinical value unless they are shown to work in other samples.
Altman, D +3 more
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EarlyR: A Robust Gene Expression Signature for Predicting Outcomes of Estrogen Receptor–Positive Breast Cancer [PDF]
Introduction Early stage estrogen receptor (ER)-positive breast cancer may be treated with chemotherapy in addition to hormone therapy. Currently available molecular signatures assess the risk of recurrence and the benefit of chemotherapy; however ...
Badve, Sunil S. +2 more
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Clinical Utility of Circulating Tumor Cells in Patients With Esophageal Cancer
BackgroundAs one of the most aggressive gastrointestinal tract cancers, esophageal carcinoma (EC) had the tenth morbidity and sixth mortality rate globally in 2020.
Yang Li +6 more
doaj +1 more source
Comparison of conservative treatment versus transcatheter arterial embolisation for the treatment of spontaneously ruptured hepatocellular carcinoma [PDF]
Purpose: To elucidate the prognostic factors in the spontaneous rupture of hepatocellular carcinoma (HCC) and to determine whether transcatheter arterial embolisation (TAE) is associated with better prognosis compared to conservative treatment.
Baba, Yasutaka +8 more
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The prognostic of the Remaining Useful Life (RUL) of composite structures remains a critical challenge as it involves understanding complex degradation behaviors while it is emerging for maintaining the safety and reliability of aerospace structures.
Ferda C. Gül +2 more
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Prognostic value of routine laboratory variables in prediction of breast cancer recurrence. [PDF]
The prognostic value of routine laboratory variables in breast cancer has been largely overlooked. Based on laboratory tests commonly performed in clinical practice, we aimed to develop a new model to predict disease free survival (DFS) after surgical ...
Du, Ye +10 more
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