Results 151 to 160 of about 757,160 (318)

Carcinoma papilífero de alto risco da glândula tireóide: influência dos fatores prognósticos em 126 pacientes

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: Este trabalho tem como objetivo avaliar a influência dos fatores prognósticos em portadores de carcinoma papilífero da tireóide, tratados no Hospital do Câncer (INCA-RJ). MÉTODO: Com base em testes estatísticos (Wilcoxon e Cox) foram analisados
Mauro Marques Barbosa, Geraldo Matos de Sá, Roberto R. M. de Araújo Lima, Jacob Kligerman, Terence Pires de Farias, Maurílio José Chagas   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Risk Factors and Prognostic Factors in GBC

Journal of Clinical Medicine
Background: Gallbladder cancer (GBC) is a rare entity with a poor prognosis, usually discovered late due to nonspecific symptoms; therefore, over the last years, attention has been focused on identifying the risk factors for developing this malignancy in order to provide an early diagnosis, as well as new prognostic factors in order to modulate the ...
Luiza Tirca, Catalin Savin, Cezar Stroescu, Irina Balescu, Sorin Petrea, Camelia Diaconu, Bogdan Gaspar, Lucian Pop, Valentin Varlas, Adrian Hasegan, Cristina Martac, Ciprian Bolca, Marilena Stoian, Anca Zgura, Gabriel Petre Gorecki, Nicolae Bacalbasa   +15 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Advancements in prognostic factors and survival outcomes following pulmonary metastasectomy for head and neck cancers [PDF]

Surgical treatment of lung metastases originating from head and neck tumors has shown favorable outcomes with low incidence of complications and mortality.
Vasileios Leivaditis, Athanasios Papatriantafyllou, Konstantinos Tasios, Ioannis Panagiotopoulos, Dimitrios Litsas, Anastasia Katinioti, Benjamin Ehle, Francesk Mulita, Manfred Dahm, Paraskevi Katsakiori, Elias Liolis, Konstantinos Grapatsas, Efstratios Koletsis   +12 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Prognostic Factors in Neuroblastoma

Annals of Surgery, 1971
R L, Swank, G H, Fetterman, W K, Sieber, W B, Kiesewetter   +3 more
openaire   +3 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source