Results 181 to 190 of about 757,160 (318)

Prognostic Factors in Oropharyngeal Cancer Treated With Definitive Chemoradiotherapy. [PDF]

Cancer Med
Kashid SR, Budrukkar A, Swain M, Laskar SG, Murthy V, Gupta T, Sasidharan A, Patil V, Joshi A, Noronha V, Mittal N, Mahimkar M, Patil A, Patel U, Sinha S, Kumar A, Menon N, Bal M, Prabhash K, Agarwal JP.   +19 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Mortality and prognostic factors in infective endocarditis: A Colombian multicenter cohort. [PDF]

IJID Reg
Zuluaga Monroy JD, Perez Ardila MA, Millan Prada HA, Peña Giraldo ME, Kock Sierra J, Ospina Navarro L, Arias G, Uribe LG.   +7 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Survival and prognostic factors in vaginal cancer: an analysis of 2016-2020 nationwide data. [PDF]

Int J Clin Oncol
Shigeto T, Yokoyama Y, Yamagami W, Takahashi F, Tokunaga H, Yamamoto E, Yoshino K, Kawana K, Nagase S.   +8 more
europepmc   +1 more source

Prognostic factors in IUI

JBRA Assisted Reproduction, 2019
Bahadur, Gulam, Homburg, Roy
openaire   +2 more sources

AscF in the mycobacterial CIII–CIV supercomplex lacks metal and nucleotide binding but links malate oxidation to respiration

FEBS Letters, EarlyView.
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile, Riccardo Diamanti, Daniel Lundin, Soni Sharma, Robin Lissner, Coenraad P. Kuil, Martin Högbom, Dirk Bald, Dan Sjöstrand   +8 more
wiley   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source

Prognostic factors evaluated in differentiated thyroid carcinomas. [PDF]

Endocr Connect
Ito Y, Miyauchi A.
europepmc   +1 more source