Results 61 to 70 of about 757,160 (318)

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

Sequential Allocation and Balancing Prognostic Factors in a Psychiatric Clinical Trial [PDF]

, 2008
In controlled clinical trials, each of several prognostic factors should be balanced across the trial arms. Traditional restricted randomization may be proved inadequate especially with small sample sizes.
Carlos A. B. Pereira, Basilio B. Pereira, Victor Fossaluza, Juliana B. Diniz, Euripedes C. Miguel   +4 more
core   +1 more source

Prognostic factors and outcome of pineoblastoma: 10 years single-center experience

Journal of the Egyptian National Cancer Institute, 2021
Background The survival of pineoblastoma patients is low, particularly in infants and those with metastatic disease. This study aimed to analyze the prognostic factors affecting the outcome of Pineoblastoma in different age groups.
Ahmed Elhemaly, Mohamed S. Zaghloul, Soha Ahmed, Hala Taha, Amal Refaat, Eslam Maher, Mohamed El-Beltagy, Wael Zekry   +7 more
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Prognostic factors in inpatients with advanced cancer at a palliative care unit [PDF]

, 2022
Objectives: This study aims to identify prognostic factors and their discriminatory ability in inpatients with advanced cancer at a palliative care unit (PCU).
Livia Costa de Oliveira, Raphael de Paiva Cypriano, Amanda Soares Oliveira, Karla Santos da Costa Rosa   +3 more
core   +1 more source

Prognostic Factors of Paraneoplastic Pemphigus [PDF]

Archives of Dermatology, 2012
To identify the prognostic factors of overall survival in a series of patients with paraneoplastic pemphigus (PNP).Multicenter retrospective cohort study.Twenty-seven dermatology departments in France.A total of 53 patients (31 men and 22 women; median age, 59 years; age range, 30-88 years) were diagnosed as having PNP between 1992 and 2010.Overall ...
Leger, Sandy, Picard, Damien, Ingen-Housz-Oro, Saskia, Arnault, Jean-Philippe, Aubin, François, Carsuzaa, Francis, Chaumentin, Gilles, Chevrant-Breton, Jacqueline, Chosidow, Olivier, Crickx, Béatrice, d'Incan, Michel, Dandurand, Michel, Debarbieux, Stéphane, Delaporte, Emmanuel, Dereure, Olivier, Doutre, Marie-Sylvie, Guillet, Gérard, Jullien, Denis, Kupfer, Ingrid, Lacour, Jean-Philippe, Leonard, Fabienne, Lok, Catherine, Machet, Laurent, Martin, Ludovic, Paul, Carle F, Pignon, Jean-Michel, Robert, Caroline, Thomas, Luc, Weiller, Pierre-Jean, Ferranti, Vincent, Gilbert, Danièle, Courville, Philippe, Houivet, Estelle, Benichou, Jacques, Joly, Pascal   +34 more
openaire   +4 more sources

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Evaluating the Quality of Research into a Single Prognostic Biomarker: A Systematic Review and Meta-analysis of 83 Studies of C-Reactive Protein in Stable Coronary Artery Disease [PDF]

, 2010
Background: Systematic evaluations of the quality of research on a single prognostic biomarker are rare. We sought to evaluate the quality of prognostic research evidence for the association of C-reactive protein (CRP) with fatal and nonfatal events ...
Adam D Timmis, Kate S L McAllister, Fitzpatrick Natalie K., J. Damant (7608818), Stephen Palmer, McAllister, Kate, Aroon D Hingorani, A. D. Timmis (7608830), Hingorani, AD, Chen Ruoling, A. D. Hingorani (7602500), Damant Jacqueline, Fitzpatrick, NK, Timmis Adam D., Keith R. Abrams, J. C. Kaski (7608827), Palmer, S, Fitzpatrick, Natalie K., Chen, Ruoling, Abrams, Keith R, Harry Hemingway, Timmis, Adam D, Philipson, P, Santiago Moreno, Natalie K. Fitzpatrick, Palmer, Stephen, Turnbull, Fiona Mary, McAllister, Kate S L, Damant, J, Timmis, Adam D., K. S. L. McAllister (7608824), Moreno, Santiago, Kaski, JC, Philipson Peter, Hingorani, Aroon D, Hemingway Harry, Adam D. Timmis, Fitzpatrick, Natalie K, Abrams Keith R., Keith R. Abrams (7579436), Shipley, Martin, Palmer Stephen, Hemingway, Harry, Shipley Martin, Abrams, Keith R., Chen, R, H. Hemingway (7608809), McAllister, KSL, Shipley, M, Timmis, AD, Moreno Santiago, Natalie K Fitzpatrick, Hingorani Aroon D., Damant, Jacqueline, Juan Carlos Kaski, Fitzpatrick, Natalie, Philipson, Peter, McAllister, KS, N. K. Fitzpatrick (7608815), Kaski Juan Carlos, P. Philipson (7608812), Abrams, Keith, Kate S. L. McAllister, S. Palmer (3693193), Martin Shipley, Peter Philipson, Jacqueline Damant, M. Shipley (7608821), McAllister Kate S. L., Santiago Moreno (90184), Chen, RL, Moreno, S, Mcallister, Katherine, Abrams, KR, R. Chen (576618), Hingorani, Aroon D., Kaski, Juan Carlos, Keith R Abrams, Hemingway, H, Timmis, Adam, Aroon D. Hingorani, Ruoling Chen, Philipson, Pete, Hingorani, Aroon   +83 more
core   +1 more source

Risk factors and poor prognostic factors of preeclampsia in Ibn Rochd University Hospital of Casablanca: about 401 preeclamptic cases

The Pan African Medical Journal, 2018
Preeclampsia is a gestational pathology that complicates 2 to 8% of pregnancies and is one of the major causes of maternal and fetal morbidity and mortality worldwide.
Meriem Benfateh, Souadou Cissoko, Houssine Boufettal, Jean-Jacques Feige, Naima Samouh, Touria Aboussaouira, Mohamed Benharouga, Nadia Alfaidy   +7 more
doaj   +1 more source

Health Literacy, Self‐Efficacy and Knowledge of Sickle Cell Disease Among Caregivers

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a hereditary blood disorder in which abnormal haemoglobin leads to severe anaemia, painful crises and organ failure. Caregivers’ health literacy (HL) – their ability to assess, understand and apply information, and interact with healthcare professionals – is crucial for managing children with SCD, yet ...
Melanie Bruinooge, Maite E. Houwing, Rowena L. Grohssteiner, Ferdows Atiq, Sonja A. M. C. Teuben, Mirjam P. Fransen, Marjon H. Cnossen   +6 more
wiley   +1 more source