Results 31 to 40 of about 53,579 (265)

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source

Real‐World Insights Into the Clinical Characteristics and Survival Outcomes of Extranodal Peripheral T‐Cell Lymphomas: A Multiethnic Asian Cohort Study

eJHaem
Background Extranodal peripheral T‐cell lymphomas (PTCLs) comprise a diverse group of lymphomas whose real‐world presentation and course are infrequently studied.
Ryan Yee Shien Neo, Esther Wei Yin Chang, Soon Thye Lim, Jason Yongsheng Chan   +3 more
doaj   +1 more source

Delta-Procalcitonin and Vitamin D Can Predict Mortality of Internal Medicine Patients with Microbiological Identified Sepsis

Medicina, 2021
Background: The management of septic patients hospitalized in Internal Medicine wards represents a challenge due to their complexity and heterogeneity, and a high mortality rate.
Alberto Tosoni, Anthony Cossari, Mattia Paratore, Michele Impagnatiello, Giovanna Passaro, Carla Vincenza Vallone, Vincenzo Zaccone, Antonio Gasbarrini, Giovanni Addolorato, Salvatore De Cosmo, Antonio Mirijello, on behalf of the Internal Medicine Sepsis Study Group   +11 more
doaj   +1 more source

Reconciliation of sampling data and heterogeneity analysis of a bauxite mine in Poços de Caldas/MG, in Brazil

REM: International Engineering Journal, 2020
Reconciliation plays a key role in controlling and analysing mine operations. It consists in comparing model estimates with actual results produced by the plant, being used as an indicator, a monitoring tool. Discrepancies between these values are common
Felipe Expedito Martins Alves, Beatriz Alexandra de Souza, Daniel Armelim Bortoleto, Thammiris Mohamad El Hajj   +3 more
doaj   +1 more source

HIV‐associated Burkitt lymphoma in the combination antiretroviral therapy era: Real‐world outcomes and prognostication

eJHaem, 2023
We performed a retrospective study to analyze the clinical characteristics and outcomes of human immunodeficiency virus–associated Burkitt's lymphoma in Chongqing University Cancer Hospital, southwest China, from March 2012 to February 2022.
Chaoyu Wang, Shunsi Liang, Xi Quan, Bingling Guo, Dehong Huang, Jieping Li, Yao Liu   +6 more
doaj   +1 more source

Machine Learning Use for Prognostic Purposes in Multiple Sclerosis

Life, 2021
The course of multiple sclerosis begins with a relapsing-remitting phase, which evolves into a secondarily progressive form over an extremely variable period, depending on many factors, each with a subtle influence. To date, no prognostic factors or risk
Ruggiero Seccia, Silvia Romano, Marco Salvetti, Andrea Crisanti, Laura Palagi, Francesca Grassi   +5 more
doaj   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Technology of prognostication of sporting achievements of badminton players on the stage of preliminary base preparation. [PDF]

Pedagogìka, Psihologìâ ta Mediko-bìologìčnì Problemi Fìzičnogo Vihovannâ ì Sportu, 2011
In the article the technology of evaluation of potential capabilities of badminton players is displayed 12-14 years. The functional, pedagogical and psychophysiological criteria which became a component parts of the developed analytical models of ...
Shyyan V.N., Shamardin V.N.
doaj