Results 71 to 80 of about 65,493 (306)
Standards for Studies of Neurological Prognostication in Comatose Survivors of Cardiac Arrest: A Scientific Statement from the American Heart Association [PDF]
Significant improvements have been achieved in cardiac arrest resuscitation and postarrest resuscitation care, but mortality remains high. Most of the poor outcomes and deaths of cardiac arrest survivors have been attributed to widespread brain injury ...
Sandroni C.
core +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Research Progress on Predictive Biomarkers of Immunotherapy Efficacy in Non-small Cell Lung Cancer
Lung cancer is one of the most common malignant tumors in the world, of which non-small cell lung cancer (NSCLC) is the majority. The emergence of immune checkpoint inhibitors (ICIs) has greatly changed the treatment strategy of NSCLC and improved the ...
Tiansheng SUN +3 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Prognostication Decision Tree Tutorial
To recognise the important factors needed to make a judgement about a patient’s stage of disease and prognosis. To apply this knowledge when making treatment decisions.
University of Bristol
core
Prognostication of receipts of value added tax in a budget
Цель статьи состоит в разработке методического подхода к прогнозированию поступлений НДС в государственный бюджет Украины, позволяющего повысить оперативность и объективность прогнозирования в сочетании с уменьшением объемов необходимой для ...
Охтень, А.А. +1 more
core +1 more source
The Tumor Microenvironment of DLBCL in the Computational Era
Among classical exemplifications of tumor microenvironment (TME) in lymphoma pathogenesis, the “effacement model” resembled by diffuse large B cell lymphoma (DLBCL) implies strong cell autonomous survival and paucity of non-malignant elements ...
Giuseppina Opinto +8 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
"STRATEGIC PROGNOSTICATION OF INTERNATIONAL RELATIONS"
Book review: Strategic prognostication of international relations: the count. monograph / ed. A.I., Podberezkin, M.V. Aleksandrov; [A. Podberezkin I. et al.]; Moscow State Institute of International Relations (University), Ministry of Foreign Affairs of ...
E. T. Mekhdiev
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source

