Results 81 to 90 of about 6,757 (297)

Performance Data Prognostics Based on Relevance Vector Machine and Particle Filter

open access: yesChemical Engineering Transactions, 2013
Prognostics of equipment state is one of the most important and difficult issue in Prognostics and Health Management (PHM) technology. In this paper, Relevance Vector Machine (RVM) and Particle Filter (PF) are used to analyse equipment state and predict ...
Y. Hu, P. Luo
doaj   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A combined sensitivity analysis and kriging surrogate modeling for early validation of health indicators [PDF]

open access: yes, 2014
To increase the dependability of complex systems, one solution is to assess their state of health continuously through the monitoring of variables sensitive to potential degradation modes. When computed in an operating environment, these variables, known
MECHBAL, Nazih   +2 more
core   +1 more source

Real-Time AI-Driven Prognostics and Health Management in Robotics

open access: yesApplied Sciences
The increasing deployment of robotic systems in complex and high-stakes environments, such as advanced manufacturing, healthcare, space exploration, and service robotics, requires robust strategies to ensure operational reliability, safety, and ...
Mohad Tanveer   +3 more
doaj   +1 more source

A Hybrid LSSVR/HMM-Based Prognostic Approach

open access: yesSensors, 2013
In a health management system, prognostics, which is an engineering discipline that predicts a system’s future health, is an important aspect yet there is currently limited research in this field.
Xianhui Liu   +3 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Battery Prognostics and Health Management: AI and Big Data

open access: yesWorld Electric Vehicle Journal
In the Industry 4.0 era, integrating artificial intelligence (AI) with battery prognostics and health management (PHM) offers transformative solutions to the challenges posed by the complex nature of battery systems.
Di Li   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

open access: yesMolecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard   +8 more
wiley   +1 more source

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