Results 111 to 120 of about 15,777,155 (294)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Town of Chester Stormwater Management Project [PDF]
, 2008 Great Bay Environmental Consulting (GBEC) worked with the Town of Chester Planning Board to improve regulatory approaches to stormwater management.
NHEP Community Technical Assistance Program
core +2 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Gravimetric Soil Moisture Protocols [PDF]
, 2003 The purpose of this resource is to measure soil water content by mass. Students collect soil samples with a trowel or auger and weigh them, dry them, and then weigh them again.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Defining Regional Boundaries [PDF]
, 2003 The purpose of this resource is to identify a reqion for study as a system, and to establish a list of characteristics and features useful for determining the boundaries of regional systems.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
, 2003 The purpose of this resource is to observe plant green-down and report greendown data to help validate estimates of the end of the plant growing season. Students monitor the change in color of selected leaves of trees, shrubs or grasses.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core