Results 141 to 150 of about 15,777,155 (294)
Studying the Instrument Shelter [PDF]
, 2003 The purpose of this activity is to discover why an instrument shelter is built the way it is. Students construct shelters that have varying properties and place them in the same location or place similar shelters in different locations and compare ...
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core
Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery, 2019 openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Seasonal Change on Land and Water [PDF]
, 2003 The purpose of this resource is to further students' understanding of the causes of seasonal change using visualizations to compare the effects of incoming solar energy in the two hemispheres.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Conclave: writing programs to understand programs
, 2014 Software maintainers are often challenged with source code changes to improve software systems, or eliminate defects, in unfamiliar programs. To undertake these tasks a sufficient understanding of the system, or at least a small part of it, is required.
Carvalho, Nuno Ramos +3 more
openaire +4 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Practicing Your Protocols [PDF]
, 2003 The purpose of this resource is to have students learn to use the hydrology instruments and collect the hydrology data accurately. In the classroom, students practice using the instruments or kits for protocols, exploring the range of measurements and ...
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Site Seeing Intermediate Level [PDF]
, 2003 The purpose of this resource is to investigate the idea that every dynamic system has energy and matter in different forms.
The GLOBE Program, University Corporation for Atmospheric Research (UCAR)
core
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source